{
  "id": 16150,
  "label": "Feingold syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015267",
  "properties": {
    "xrefs": [
      "DOID:0060464",
      "GARD:0008407",
      "MEDGEN:163209",
      "NCIT:C74987",
      "OMIMPS:164280",
      "Orphanet:1305",
      "UMLS:C0796068"
    ],
    "synonyms": [
      "Brunner-Winter syndrome",
      "FGLDS",
      "FS",
      "MMT",
      "MODED syndrome",
      "ODED syndrome",
      "digital anomalies with short palpebral fissures and atresia of esophagus or duodenum",
      "digital anomalies with short palpebral fissures and atresia of oesophagus or duodenum",
      "microcephaly-digital anomalies-normal intelligence syndrome",
      "microcephaly-intellectual disability-tracheoesophageal fistula syndrome",
      "microcephaly-oculo-digito-esophageal-duodenal syndrome syndrome",
      "oculo-digito-esophageal-duodenal syndrome",
      "digital anomalies with short palpebral fissures and atresia of esophagus, or duodenum"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      }
    ],
    "definition": "Feingold syndrome (FS), also known as oculo-digito-esophageal-duodenal (ODED) syndrome, is a rare inherited malformation syndrome characterized by microcephaly, short stature and numerous digital anomalies and is comprised of two subtypes: FS type 1 (FS1) and FS type 2 (FS2). FS1 is by far the most common form while FS2 has only been reported in 3 patients and has the same clinical characteristics as FS1, apart from the absence of gastrointestinal atresia and short palpebral fissures."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 2903,
      "label": "autosomal dominant disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2905
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050736",
          "ICD9:758.5",
          "MEDGEN:539206",
          "SCTID:11164009",
          "UMLS:C0265385"
        ],
        "synonyms": [
          "autosomal dominant disease or disorder",
          "autosomal dominant hereditary disorder",
          "autosomal dominant inherited disorder",
          "disease or disorder, autosomal dominant",
          "disease, autosomal dominant"
        ],
        "definition": "Autosomal dominant form of disease."
      },
      "child_count": 192,
      "reference_id": "MONDO:0000426"
    },
    {
      "id": 4370,
      "label": "syndromic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:225",
          "MEDGEN:11688",
          "MESH:D013577",
          "NCIT:C28193",
          "OGMS:0000086",
          "UMLS:C0039082"
        ],
        "synonyms": [
          "cluster, symptom",
          "clusters, symptom",
          "symptom cluster",
          "symptom clusters",
          "syndrome",
          "syndrome associated with disease or disorder",
          "syndromes",
          "syndromic disease",
          "syndromic disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition."
      },
      "child_count": 1182,
      "reference_id": "MONDO:0002254"
    }
  ],
  "children": [
    {
      "id": 9431,
      "label": "Feingold syndrome type 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16150
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017624",
          "ICD9:759.89",
          "MEDGEN:1637716",
          "OMIM:164280",
          "Orphanet:391641",
          "SCTID:702431004",
          "UMLS:C4551774"
        ],
        "synonyms": [
          "Brunner-Winter syndrome type 1",
          "FGLDS1",
          "FS1",
          "Feingold syndrome caused by mutation in MYCN",
          "Feingold syndrome type 1",
          "MMT type 1",
          "MODED syndrome type 1",
          "MYCN Feingold syndrome",
          "ODED syndrome type 1",
          "digital anomalies with short palpebral fissures and atresia of esophagus or duodenum type 1",
          "digital anomalies with short palpebral fissures and atresia of oesophagus or duodenum type 1",
          "microcephaly-digital anomalies-normal intelligence syndrome type 1",
          "microcephaly-intellectual disability-tracheoesophageal fistula syndrome type 1",
          "microcephaly-oculo-digito-esophageal-duodenal syndrome syndrome type 1",
          "oculo-digito-esophageal-duodenal syndrome type 1",
          "Feingold syndrome",
          "Feingold syndrome 1",
          "Mmt syndrome",
          "Oded syndrome",
          "digital anomalies with short palpebral fissures and atresia of esophagus or duodenum",
          "digital anomalies with short palpebral fissures and atresia of oesophagus or duodenum",
          "microcephaly and digital abnormalities with normal intelligence",
          "microcephaly, intellectual disability, and tracheoesophageal fistula syndrome",
          "microcephaly, mental retardation, and tracheoesophageal fistula syndrome",
          "microcephaly-oculo-digito-esophageal-duodenal syndrome",
          "oculodigitoesophagoduodenal syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "Feingold syndrome type 1 (FS1) is a rare inherited malformation syndrome characterized by microcephaly, short stature and numerous digital anomalies."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008115"
    },
    {
      "id": 14713,
      "label": "Feingold syndrome type 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16150
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017625",
          "MEDGEN:482119",
          "OMIM:614326",
          "Orphanet:391646",
          "UMLS:C3280489"
        ],
        "synonyms": [
          "Brunner-Winter syndrome type 2",
          "FGLDS2",
          "FS2",
          "Feingold syndrome type 2",
          "MMT type 2",
          "brachydactyly-short stature-microcephaly syndrome",
          "microcephaly-digital anomalies-normal intelligence syndrome type 2",
          "microcephaly-intellectual disability-tracheoesophageal fistula syndrome type 2",
          "Feingold syndrome 2",
          "brachydactyly with short stature and microcephaly"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "Feingold syndrome type 2 (FS2) is a rare inherited malformation syndrome characterized by skeletal abnormalities and mild intellectual disabilities similar to those seen in Feingold syndrome type 1 (FS1) but that lacks the manifestations of gastrointestinal atresia and short palpebral fissures."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013691"
    }
  ],
  "roots": [
    {
      "id": 2903,
      "label": "autosomal dominant disease"
    },
    {
      "id": 4370,
      "label": "syndromic disease"
    }
  ]
}