{
  "id": 16169,
  "label": "herpes simplex virus keratitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015288",
  "properties": {
    "xrefs": [
      "DOID:0080158",
      "EFO:0007308",
      "GARD:0025063",
      "MEDGEN:5534",
      "NCIT:C34743",
      "Orphanet:137586",
      "SCTID:9389005",
      "UMLS:C0019357"
    ],
    "synonyms": [
      "HSV keratitis",
      "Simplexvirus caused keratitis",
      "Simplexvirus keratitis",
      "dendritic keratitis",
      "herpetic keratitis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "A superficial, epithelial Herpesvirus hominis infection of the cornea, characterized by the presence of small vesicles which may break down and coalesce to form dendritic ulcers (keratitis, dendritic). (Dictionary of Visual Science, 3d ed)"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6399,
      "label": "herpes simplex infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7411
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8566",
          "EFO:1002022",
          "ICD10CM:B00",
          "ICD9:054",
          "ICD9:058.89",
          "MEDGEN:9234",
          "MESH:D006561",
          "SCTID:88594005",
          "UMLS:C0019348"
        ],
        "synonyms": [
          "Simplexvirus caused disease or disorder",
          "Simplexvirus disease or disorder",
          "Simplexvirus infectious disease",
          "herpes simplex",
          "herpes simplex complex",
          "herpes simplex infection",
          "herpes simplex viral infection"
        ],
        "definition": "A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)"
      },
      "child_count": 10,
      "reference_id": "MONDO:0004609"
    },
    {
      "id": 20248,
      "label": "viral eye infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6834,
        23257
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:8753",
          "MESH:D015828",
          "SCTID:312132001",
          "UMLS:C0015407"
        ],
        "synonyms": [
          "viral eye infection",
          "EYE INFECT VIRAL",
          "Eye Infection, Viral",
          "Eye Infections, Viral",
          "Infection, Viral Eye",
          "Infection, Viral Ocular",
          "Infections, Viral Eye",
          "Infections, Viral Ocular",
          "OCULAR INFECT VIRAL",
          "Ocular Infection, Viral",
          "Ocular Infections, Viral",
          "VIRAL EYE INFECT",
          "Viral Eye Infection",
          "Viral Eye Infections",
          "Viral Ocular Infection",
          "Viral Ocular Infections",
          "Viral eye infection"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Infections of the eye caused by minute intracellular agents. These infections may lead to severe inflammation in various parts of the eye - conjunctiva, iris, eyelids, etc. Several viruses have been identified as the causative agents. Among these are Herpesvirus, Adenovirus, Poxvirus, and Myxovirus."
      },
      "child_count": 10,
      "reference_id": "MONDO:0020950"
    },
    {
      "id": 21277,
      "label": "corneal infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5071,
        16683
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:152673",
          "NCIT:C83813",
          "Orphanet:519278",
          "SCTID:312428002",
          "UMLS:C0729777"
        ],
        "synonyms": [
          "corneal infection",
          "infection of cornea",
          "infective keratitis",
          "keratitis caused by infection"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A viral or bacterial infectious process affecting the cornea. Symptoms include pain and redness in the eye, photophobia and eye watering."
      },
      "child_count": 14,
      "reference_id": "MONDO:0023865"
    }
  ],
  "children": [
    {
      "id": 16172,
      "label": "stromal keratitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16169
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019879",
          "MEDGEN:727306",
          "Orphanet:137599",
          "UMLS:C1318020",
          "icd11.foundation:1665288755"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Herpes simplex (HSV) stromal keratitis is an infectious ocular disease of either necrotizing or non-necrotizing form, due to an HSV infection, and characterized by corneal stromal necrosis, inflammation, ulceration and infiltration by leukocytes. Corneal perforation and blindness can also occur in severe cases."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015291"
    },
    {
      "id": 16173,
      "label": "endotheliitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16169
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019880",
          "MEDGEN:602202",
          "Orphanet:137602",
          "UMLS:C0423262",
          "icd11.foundation:1363910196"
        ],
        "synonyms": [
          "endothelium inflammation",
          "inflammation of endothelium"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "An inflammatory disease involving a pathogenic inflammatory response in the endothelium."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015292"
    }
  ],
  "roots": [
    {
      "id": 6399,
      "label": "herpes simplex infectious disease"
    },
    {
      "id": 20248,
      "label": "viral eye infection"
    },
    {
      "id": 21277,
      "label": "corneal infection"
    }
  ]
}