{
  "id": 16269,
  "label": "cleft lip and alveolus",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015420",
  "properties": {
    "xrefs": [
      "GARD:0016976",
      "ICD9:525.8",
      "MEDGEN:720590",
      "Orphanet:141291",
      "SCTID:373643003",
      "UMLS:C1298692",
      "icd11.foundation:1653169553"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "Cleft lip and alveolus is a fissure type embryopathy that involves the upper lip, nasal base and alveolar ridge in variable degrees."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 2863,
      "label": "orofacial cleft",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        21213
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050567",
          "MEDGEN:472000",
          "OMIMPS:119530",
          "SCTID:449790007",
          "UMLS:C3266076"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A disorder of facial skeleton that is characterized by cleft lip and/or cleft palate that result in feeding, speech and hearing problems caused by failures during development."
      },
      "child_count": 32,
      "reference_id": "MONDO:0000358"
    },
    {
      "id": 20383,
      "label": "disorder of development or morphogenesis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:Q00-Q99",
          "MEDGEN:1843482",
          "UMLS:C0694457"
        ],
        "definition": "Any disease or disorder that disrupts the process development of an anatomical structure. Can be due to genetic or environmental causes. Typically happens during embryogenesis, but also includes post-embryonic development."
      },
      "child_count": 190,
      "reference_id": "MONDO:0021147"
    }
  ],
  "children": [
    {
      "id": 13206,
      "label": "orofacial cleft 5",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16269,
        16679,
        16680
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080399",
          "GARD:0018305",
          "MEDGEN:373280",
          "MESH:C563843",
          "OMIM:608874",
          "UMLS:C1837210"
        ],
        "synonyms": [
          "MSX1 orofacial cleft",
          "orofacial cleft 5",
          "orofacial cleft caused by mutation in MSX1",
          "orofacial cleft type 5",
          "OFC5",
          "cleft lip with or without cleft palate, nonsyndromic, 5"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Any orofacial cleft in which the cause of the disease is a mutation in the MSX1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012142"
    }
  ],
  "roots": [
    {
      "id": 2863,
      "label": "orofacial cleft"
    },
    {
      "id": 20383,
      "label": "disorder of development or morphogenesis"
    }
  ]
}