{
  "id": 16307,
  "label": "cranio-osteoarthropathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015466",
  "properties": {
    "xrefs": [
      "GARD:0001564",
      "MEDGEN:394824",
      "Orphanet:1525",
      "SCTID:720753002",
      "UMLS:C2678439",
      "icd11.foundation:225223076"
    ],
    "synonyms": [
      "Currarino disease",
      "Currarino idiopathic osteoarthropathy",
      "Reginato-Schiapachasse syndrome",
      "cranio osteoarthropathy"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      }
    ],
    "definition": "Cranio-osteoarthropathy (COA) is a form of primary hypertrophic osteoarthropathy characterized by delayed closure of the cranial sutures and fontanels, digital clubbing, arthropathy, and periostosis."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 17104,
      "label": "primary hypertrophic osteoarthropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        5714
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14283",
          "GARD:0020667",
          "MEDGEN:18210",
          "MESH:D010004",
          "MedDRA:10051686",
          "NANDO:1200642",
          "NANDO:2100288",
          "NANDO:2201004",
          "NCIT:C85023",
          "OMIMPS:259100",
          "Orphanet:248095",
          "Orphanet:2796",
          "SCTID:88220006",
          "UMLS:C0029411",
          "icd11.foundation:792225761"
        ],
        "synonyms": [
          "PDP",
          "PHO",
          "Touraine Solente Gole syndrome",
          "Touraine-Solente-Gole syndrome",
          "hypertrophic osteoarthropathy, primary",
          "hypertrophic osteoarthropathy, primary, autosomal recessive, type 1",
          "hypertropic osteoarthropathy, primary",
          "idiopathic hypertrophic osteoarthropathy",
          "pachydermoperiostosis",
          "pachydermoperiostosis of nail [ambiguous]",
          "PHOAR1",
          "hypertrophic osteoarthropathy, primary, autosomal recessive, 1"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A genetically and clinically heterogeneous inherited disorder characterized by digital clubbing and osteoarthropathy, with variable features of pachydermia, delayed closure of the fontanels, and congenital heart disease. There are two types of PHO: pachydermoperiostosis and cranio-osteoarthropathy."
      },
      "child_count": 8,
      "reference_id": "MONDO:0016620"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 17104,
      "label": "primary hypertrophic osteoarthropathy"
    }
  ]
}