{
  "id": 16344,
  "label": "trigeminal autonomic cephalalgia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015530",
  "properties": {
    "xrefs": [
      "GARD:0020017",
      "ICD9:339.09",
      "MEDGEN:327950",
      "MESH:D051303",
      "NCIT:C117074",
      "Orphanet:157843",
      "SCTID:449814007",
      "UMLS:C1565172",
      "icd11.foundation:607078588"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A headache disorder characterized by episodes of unilateral, short lasting pain and associated ipsilateral cranial autonomic symptoms."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 5448,
      "label": "trigeminal nerve disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5469,
        5512
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:561",
          "EFO:0009569",
          "ICD9:350.8",
          "MEDGEN:101823",
          "MESH:D020433",
          "NCIT:C26952",
          "SCTID:64309007",
          "UMLS:C0152177"
        ],
        "synonyms": [
          "disease of trigeminal nerve",
          "disease or disorder of trigeminal nerve",
          "disorder of trigeminal nerve",
          "trigeminal nerve disease",
          "trigeminal nerve disease or disorder",
          "trigeminal nerve disorder",
          "disorder of the fifth cranial nerve",
          "disorders of the fifth nerve",
          "disorders of the vth cranial nerve"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disease involving the trigeminal nerve."
      },
      "child_count": 8,
      "reference_id": "MONDO:0003543"
    },
    {
      "id": 17523,
      "label": "hypnic headache",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010796",
          "HP:0012459",
          "ICD10CM:G44.81",
          "ICD9:339.81",
          "MEDGEN:156012",
          "MESH:D051270",
          "Orphanet:276429",
          "SCTID:122711000119109",
          "UMLS:C0752150",
          "icd11.foundation:468065426"
        ],
        "synonyms": [
          "hypnic headache",
          "hypnic headache (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Conditions in which the primary symptom is headache and the headache cannot be attributed to any known causes."
      },
      "child_count": 2,
      "reference_id": "MONDO:0017181"
    },
    {
      "id": 23165,
      "label": "neurovascular disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6799,
        7065
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:857738",
          "NCIT:C117007",
          "UMLS:C3898144"
        ],
        "synonyms": [
          "disease of nervous system vasculature",
          "nervous system disorder of vasculature",
          "neurovascular disorder",
          "vasculature nervous system disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disorder of the nervous system related to a vascular etiology."
      },
      "child_count": 58,
      "reference_id": "MONDO:0043218"
    }
  ],
  "children": [
    {
      "id": 16343,
      "label": "paroxysmal Hemicrania",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16344
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001822",
          "GARD:0010794",
          "ICD9:339.03",
          "MEDGEN:235603",
          "MESH:D051302",
          "MedDRA:10019461",
          "Orphanet:157835",
          "SCTID:443094001",
          "UMLS:C1399352",
          "icd11.foundation:959737563"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Paroxysmal hemicrania (PH) is a primary headache disorder characterized by multiple attacks of unilateral pain that occur in association with cranial autonomic symptoms. The hallmarks of this syndrome are the relative shortness of the attacks and the complete response to indomethacin therapy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015529"
    },
    {
      "id": 18616,
      "label": "hemicrania continua",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16344
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010795",
          "ICD10CM:G44.51",
          "ICD9:339.41",
          "MEDGEN:748511",
          "Orphanet:443070",
          "SCTID:443095000",
          "UMLS:C2349425",
          "icd11.foundation:1093161847"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Hemicrania continua (HC) is a type of primary headache disorder, which means the headache is not caused by another medical condition. Symptoms of HC include constant mild to moderate pain on one side of the head (unilateral) with periods of more intense, severe, migraine -like pain (exacerbations). These severe pain periods can last from 20 minutes to days. The frequency of exacerbations also varies greatly. The headache stays on the same side of the head and usually without pain free periods. HC is more common in women and most often starts in adulthood, but may begin anywhere from 5 to 67 years of age. Diagnosis of hemicrania continua (HC) is made by ruling out other possible causes of the pain and by clinical symptoms. During the periods of severe pain, at least one of the following symptoms must be present on same side of the body as the headache: watering or red eyes (conjunctival injection), congested or runny nose, or drooping eyelid. In addition, the headache pain must respond to treatment with indomethacin. The cause of HC is unknown. Other treatments for those who cannot tolerate long term indomethacin therapy are being studied."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018615"
    },
    {
      "id": 18851,
      "label": "SUNCT syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        16344
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009257",
          "MEDGEN:224724",
          "MESH:D050798",
          "MedDRA:10061981",
          "NCIT:C85174",
          "Orphanet:57145",
          "SCTID:725058003",
          "UMLS:C1262087"
        ],
        "synonyms": [
          "SUNCT headache",
          "short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing",
          "short-lasting, unilateral, neuralgiform headache attacks with conjunctival injection and tearing"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "SUNCT syndrome (Short-lasting Unilateral Neuralgiform headache attacks with Conjunctival injection and Tearing) is a primary headache disorder characterized by unilateral trigeminal pain that occurs in association with ipsilateral cranial autonomic symptoms (conjunctival injection and tearing)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018927"
    },
    {
      "id": 23224,
      "label": "cluster headache syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7209,
        16344
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:3503",
          "MESH:D003027",
          "NCIT:C117077",
          "Orphanet:1002",
          "SCTID:193031009",
          "UMLS:C0009088",
          "icd11.foundation:760621151"
        ],
        "synonyms": [
          "Cephalgia, histamine",
          "Cephalgias, histamine",
          "Horton headache",
          "Horton syndrome",
          "Horton's headache",
          "Horton's neuralgia",
          "Horton's syndrome",
          "Hortons syndrome",
          "ciliary neuralgia",
          "ciliary neuralgias",
          "cluster headache",
          "cluster headache syndrome",
          "cluster migraine",
          "erythromelalgia of the head",
          "erythroprosopalgia of bing",
          "histamine cephalgia",
          "histamine cephalgias",
          "histamine headache",
          "migraine, neuralgic",
          "migraines, neuralgic",
          "migrainous neuralgia",
          "red migraine",
          "atypical cluster headache",
          "atypical cluster headaches",
          "beuralgias, ciliary",
          "chronic cluster headache",
          "chronic cluster headaches",
          "cluster headache syndromes",
          "cluster headache, atypical",
          "cluster headache, chronic",
          "cluster headache, episodic",
          "cluster headaches",
          "cluster headaches, atypical",
          "cluster headaches, chronic",
          "cluster headaches, episodic",
          "episodic cluster headache",
          "episodic cluster headaches",
          "headache syndrome, cluster",
          "headache syndromes, cluster",
          "headache, atypical cluster",
          "headache, chronic cluster",
          "headache, cluster",
          "headache, episodic cluster",
          "headaches, atypical cluster",
          "headaches, chronic cluster",
          "headaches, cluster",
          "headaches, episodic cluster",
          "neuralgia, ciliary",
          "neuralgic migraine",
          "neuralgic migraines",
          "syndrome, Horton",
          "syndrome, Horton's",
          "syndrome, cluster headache",
          "syndromes, cluster headache",
          "vasomotor headache"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A headache disorder that is characterized by periodic severe, unilateral orbital, supraorbital, and/or temporal pain, and is associated with ipsilateral cranial autonomic symptoms."
      },
      "child_count": 2,
      "reference_id": "MONDO:0043537"
    }
  ],
  "roots": [
    {
      "id": 5448,
      "label": "trigeminal nerve disorder"
    },
    {
      "id": 17523,
      "label": "hypnic headache"
    },
    {
      "id": 23165,
      "label": "neurovascular disorder"
    }
  ]
}