{
  "id": 16382,
  "label": "Hb Bart's hydrops fetalis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015579",
  "properties": {
    "xrefs": [
      "GARD:0016992",
      "ICD9:282.49",
      "MEDGEN:543726",
      "Orphanet:163596",
      "SCTID:5300004",
      "UMLS:C0272005"
    ],
    "synonyms": [
      "Alpha-thalassemia major",
      "HBA1;HBA2 digenic quadallelic Hb Bart’s hydrops fetalis",
      "Haemoglobin Bart's hydrops fetalis",
      "Hb Bart’s hydrops fetalis caused by quadallelic variation in HBA1;HBA2",
      "Hb Bart’s hydrops fetalis related to quadallelic variation in HBA1 and HBA2",
      "Hemoglobin Bart's hydrops fetalis",
      "alpha-thalassemia hydrops fetalis",
      "homozygous alpha0-thalassemia"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Alpha thalassemia caused by variation in all four copies of the alpha hemoglobin genes (e.g., homozygous deletion encompassing HBA1 and HBA2)."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 10601,
      "label": "non-immune hydrops fetalis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16105
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017580",
          "ICD9:778.0",
          "MEDGEN:105327",
          "NCIT:C111905",
          "OMIM:236750",
          "Orphanet:363999",
          "SCTID:276509008",
          "UMLS:C0455988",
          "icd11.foundation:1182287637"
        ],
        "synonyms": [
          "non-immune HF",
          "non-immune fetal edema",
          "non-immune fetal hydrops",
          "non-immune foetal hydrops",
          "non-immune foetal oedema",
          "Haemoglobin H hydrops fetalis syndrome",
          "Hemoglobin H hydrops fetalis syndrome",
          "NIHF",
          "hydrops fetalis, Alpha-thalassemia-related",
          "hydrops fetalis, nonimmune"
        ],
        "definition": "Non-immune hydrops fetalis (NIHF), a form of HF, is a severe fetal condition defined as the excessive accumulation of fetal fluid within the fetal extravascular compartments and body cavities, and is the end-stage of a wide variety of disorders."
      },
      "child_count": 1,
      "reference_id": "MONDO:0009369"
    },
    {
      "id": 24288,
      "label": "digenic alpha thalassemia spectrum",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        12504
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026282"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An instance of alpha thalessemia spectrum that is caused by an inherited multiallelic modification in an individual."
      },
      "child_count": 3,
      "reference_id": "MONDO:0100563"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 10601,
      "label": "non-immune hydrops fetalis"
    },
    {
      "id": 24288,
      "label": "digenic alpha thalassemia spectrum"
    }
  ]
}