{
  "id": 16436,
  "label": "epilepsy syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015650",
  "properties": {
    "xrefs": [
      "GARD:0020083",
      "MEDGEN:1371141",
      "Orphanet:166463",
      "UMLS:C4505072"
    ],
    "synonyms": [
      "epileptic syndrome",
      "syndromic epilepsy"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A syndrome that has a characteristic cluster of clinical features and/or lectroencephalographic (EEG) findings that reflect underlying epileptic activity. It is often associated with a range of other health issues, including cognitive impairment, intellectual disability, physical gross motor and fine motor delays, speech and language deficits, and impacts to other bodily functions and may be supported by specific etiological findings—such as structural, genetic, metabolic, immune, or infectious causes or have an unknown etiology."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 8,
  "parents": [
    {
      "id": 6761,
      "label": "epilepsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7209
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1826",
          "EFO:0000474",
          "ICD10CM:G40",
          "ICD10WHO:G40",
          "ICD9:345",
          "ICD9:345.8",
          "ICD9:345.80",
          "ICD9:345.9",
          "ICD9:345.90",
          "ICD9:345.91",
          "MEDGEN:4506",
          "MESH:D004827",
          "NCIT:C3020",
          "SCTID:84757009",
          "UMLS:C0014544",
          "birnlex:12718"
        ],
        "synonyms": [
          "epilepsy",
          "seizure disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions."
      },
      "child_count": 13,
      "reference_id": "MONDO:0005027"
    }
  ],
  "children": [
    {
      "id": 2900,
      "label": "adolescence-adult electroclinical syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050705",
          "GARD:0027259"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An electroclinical syndrome with onset in adolescence and adulthood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000415"
    },
    {
      "id": 16311,
      "label": "benign focal seizures of adolescence",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018728",
          "MEDGEN:896830",
          "Orphanet:1544",
          "SCTID:715425000",
          "UMLS:C4275141",
          "icd11.foundation:1800285392"
        ],
        "synonyms": [
          "adolescent benign focal crisis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare epilepsy typically characterized by isolated focal motor and somatosensory seizures. Less frequently other focal seizure types, with or without secondary generalization, have been described. The seizures usually happen when the patient is awake and take a benign course. The condition is transitory, interictal examinations are normal, and there is usually no family history of epilepsy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015471"
    },
    {
      "id": 19723,
      "label": "neonatal epilepsy syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019435",
          "Orphanet:98257"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An epilepsy syndrome that has an onset during the neonatal stage of life."
      },
      "child_count": 6,
      "reference_id": "MONDO:0020070"
    },
    {
      "id": 19724,
      "label": "infantile epilepsy syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019436",
          "Orphanet:98258"
        ],
        "synonyms": [
          "epilepsy syndrome of infancy",
          "infantile epilepsy syndrome",
          "infantile onset epilepsy syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An epilepsy syndrome that occurs between 28 days to one year of life."
      },
      "child_count": 9,
      "reference_id": "MONDO:0020071"
    },
    {
      "id": 19725,
      "label": "childhood-onset epilepsy syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019437",
          "MEDGEN:1843031",
          "Orphanet:98259",
          "UMLS:C5681526"
        ],
        "synonyms": [
          "childhood epilepsy syndrome",
          "childhood-onset epilepsy syndrome",
          "epilepsy syndrome of childhood",
          "paediatric epilepsy syndrome",
          "pediatric epilepsy syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A epilepsy syndrome that occurs during childhood."
      },
      "child_count": 16,
      "reference_id": "MONDO:0020072"
    },
    {
      "id": 23780,
      "label": "neonatal/infantile epilepsy syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "Orphanet:693802"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An epilepsy sydrome that has an onset during the neonatal or infantile stage of life."
      },
      "child_count": 3,
      "reference_id": "MONDO:0100022"
    },
    {
      "id": 24301,
      "label": "myoclonic epilepsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027276",
          "MEDGEN:4988",
          "UMLS:C0014550"
        ],
        "synonyms": [
          "myoclonic epilepsy syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A group of epilepsy syndromes in which myoclonic seizures are a prominent feature."
      },
      "child_count": 7,
      "reference_id": "MONDO:0100577"
    },
    {
      "id": 24339,
      "label": "variable age epilepsy syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16436
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027372",
          "Orphanet:699645"
        ],
        "synonyms": [
          "variable age onset epilepsy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An epilepsy syndrome that has an onset during variable ages and stages of life."
      },
      "child_count": 4,
      "reference_id": "MONDO:0100619"
    }
  ],
  "roots": [
    {
      "id": 6761,
      "label": "epilepsy"
    }
  ]
}