{
  "id": 16507,
  "label": "hereditary mucosal leukokeratosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015748",
  "properties": {
    "xrefs": [
      "DOID:0050448",
      "GARD:0008501",
      "ICD9:528.6",
      "MEDGEN:328433",
      "MESH:D053529",
      "NCIT:C84760",
      "OMIMPS:193900",
      "Orphanet:171723",
      "SCTID:389203001",
      "UMLS:C1721005"
    ],
    "synonyms": [
      "White sponge nevus of Cannon",
      "hereditary mucosal leukokeratosis",
      "white sponge nevus",
      "white sponge nevus of Cannon"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "White sponge nevus (WSN) is a rare and autosomal dominant genetic disease in which the oral mucosa is white or grayish, thickened, folded, and spongy. The onset is early in life, and both sexes are affected equally. Other common sites include the tongue, floor of the mouth, and alveolar mucosa."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6801,
      "label": "melanocytic nevus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20564,
        20680
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0009675",
          "MEDGEN:14364",
          "MESH:D009506",
          "NCIT:C7570",
          "SCTID:400096001",
          "UMLS:C0027962",
          "Wikipedia:Nevus"
        ],
        "synonyms": [
          "melanocytic Nevus",
          "melanotic Nevus",
          "mole",
          "mole of skin",
          "nevus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A neoplasm composed of melanocytes that usually appears as a dark spot on the skin."
      },
      "child_count": 56,
      "reference_id": "MONDO:0005073"
    },
    {
      "id": 23867,
      "label": "hereditary skin disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6820
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MESH:D012873",
          "SCTID:239001006"
        ],
        "synonyms": [
          "disease, genetic skin",
          "diseases, genetic skin",
          "genetic skin disease",
          "genetic skin diseases",
          "genodermatosis",
          "skin disease, genetic"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An instance of skin disease that is caused by a modification of the individual's genome."
      },
      "child_count": 228,
      "reference_id": "MONDO:0100118"
    }
  ],
  "children": [
    {
      "id": 9952,
      "label": "white sponge nevus 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16507
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081287",
          "GARD:0024637",
          "MEDGEN:860363",
          "OMIM:193900",
          "UMLS:C4011926"
        ],
        "synonyms": [
          "KRT4 hereditary mucosal leukokeratosis",
          "White sponge Nevus type 1",
          "hereditary mucosal leukokeratosis caused by mutation in KRT4",
          "white sponge nevus 1",
          "WHITE sponge NEVUS 1",
          "WSN1",
          "White sponge Nevus of Cannon",
          "leukokeratosis, hereditary mucosal"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Any hereditary mucosal leukokeratosis in which the cause of the disease is a mutation in the KRT4 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008676"
    },
    {
      "id": 15348,
      "label": "white sponge nevus 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16507
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081288",
          "GARD:0016012",
          "MEDGEN:862758",
          "OMIM:615785",
          "UMLS:C4014321"
        ],
        "synonyms": [
          "White sponge Nevus type 2",
          "white sponge nevus 2",
          "WHITE sponge NEVUS 2",
          "WSN2"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0014346"
    }
  ],
  "roots": [
    {
      "id": 6801,
      "label": "melanocytic nevus"
    },
    {
      "id": 23867,
      "label": "hereditary skin disorder"
    }
  ]
}