{
  "id": 16514,
  "label": "lymphoid hemopathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015757",
  "properties": {
    "xrefs": [
      "GARD:0020131",
      "MEDGEN:1842533",
      "Orphanet:171898",
      "UMLS:C5680515"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 4440,
      "label": "hematopoietic and lymphoid system neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798,
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2531",
          "GARD:0023120",
          "MEDGEN:268180",
          "MESH:D019337",
          "NCIT:C35813",
          "SCTID:129154003",
          "UMLS:C1512393"
        ],
        "synonyms": [
          "haematopoietic neoplasm",
          "haematopoietic neoplasm (morphologic abnormality)",
          "hematologic neoplasm",
          "hematopoietic neoplasm",
          "hematopoietic neoplasm (morphologic abnormality)",
          "blood neoplasm (disease)",
          "blood tumor",
          "blood tumour",
          "haematological tumours",
          "haematopoietic and lymphoid system tumour",
          "haematopoietic system neoplasm",
          "haematopoietic system tumour",
          "haematopoietic tumours",
          "hematopoietic and lymphoid system neoplasm",
          "hematopoietic and lymphoid system tumor",
          "hematopoietic system neoplasm",
          "hematopoietic system tumor",
          "neoplasm of blood",
          "neoplasm of haematopoietic system",
          "neoplasm of hematopoietic system",
          "tumor of blood",
          "tumor of hematopoietic system",
          "tumour of blood",
          "tumour of haematopoietic system",
          "blood cancer",
          "haematopoietic cancer",
          "hematologic malignancy",
          "hematopoietic cancer",
          "malignant haematopoietic neoplasm (morphologic abnormality)",
          "malignant hematopoietic neoplasm (morphologic abnormality)",
          "hematologic cancer",
          "malignant haematopoietic neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Neoplasms of the hematopoietic system, including hematopoietic cell neoplasms (e.g. leukemias, lymphomas) and non-hematopoietic cell neoplasms that can affect the hematopoietic system (e.g. lymph node and splenic sarcomas). --2003"
      },
      "child_count": 18,
      "reference_id": "MONDO:0002334"
    }
  ],
  "children": [
    {
      "id": 6792,
      "label": "lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6881,
        16514
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060058",
          "EFO:0000574",
          "ICD9:200.0",
          "ICD9:200.1",
          "ICD9:202.80",
          "ICDO:9590/3",
          "MEDGEN:44223",
          "MESH:D008223",
          "MedDRA:10025310",
          "NANDO:2100004",
          "NCIT:C3208",
          "ONCOTREE:MLYM",
          "Orphanet:223735",
          "SCTID:118600007",
          "UMLS:C0024299"
        ],
        "synonyms": [
          "lymphoma",
          "lymphoma (Hodgkin and non-Hodgkin)",
          "lymphoma (Hodgkin's and non-Hodgkin's)",
          "lymphoma, malignant",
          "lymphomatous",
          "malignant lymphoma",
          "MLYM"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A malignant (clonal) proliferation of B- lymphocytes or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas."
      },
      "child_count": 54,
      "reference_id": "MONDO:0005062"
    },
    {
      "id": 7797,
      "label": "histiocytic and dendritic cell neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16514,
        23467
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5621",
          "EFO:1000297",
          "GARD:0019441",
          "MEDGEN:714988",
          "NCIT:C9294",
          "Orphanet:98287",
          "UMLS:C1292762"
        ],
        "synonyms": [
          "histiocytic and Dendritic cell neoplasms",
          "histiocytic and Dendritic cell tumors",
          "histiocytic and Dendritic cell tumours",
          "histiocytic and dendritic cell neoplasm",
          "histiocytic and dendritic cell",
          "histiocytic and dendritic cell cancer",
          "histiocytic and dendritic cell tumor",
          "histiocytic and dendritic cell tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Rare tumors that affect the hematopoietic and lymphoid tissues. The cells of origin are the histiocytes and accessory cells. They can occur at any age and show no significant variations in geographical distribution. This category includes the histiocytic sarcoma, Langerhans cell histiocytosis, Langerhans cell sarcoma, interdigitading dendritic cell sarcoma/tumor, follicular dendritic cell sarcoma/tumor, and dendritic cell sarcoma, not otherwise specified. (WHO, 2001)"
      },
      "child_count": 6,
      "reference_id": "MONDO:0006247"
    },
    {
      "id": 12762,
      "label": "persistent polyclonal B-cell lymphocytosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16514
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017366",
          "MEDGEN:341117",
          "MESH:C564707",
          "OMIM:606445",
          "Orphanet:300324",
          "SCTID:763864008",
          "UMLS:C1847973"
        ],
        "synonyms": [
          "PPBL",
          "persistent polyclonal B-cell lymphocytosis",
          "persistent polyclonal B-cell lymphocytosis with binucleated lymphocytes"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Persistent polyclonal B-cell lymphocytosis (PPBL) is a rare, generally benign, lymphoproliferative hematological disease characterized by: chronic, stable, persistent, polyclonal lymphocytosis of memory B-cell origin, the presence of binucleated lymphocytes in the peripheral blood, and a polyclonal increase in serum immunoglobulin M (IgM). Patients are most frequently asymptomatic or may present with mild splenomegaly."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011672"
    },
    {
      "id": 19730,
      "label": "immunodeficiency-associated lymphoproliferative disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16514
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019443",
          "MEDGEN:1843142",
          "NCIT:C150672",
          "Orphanet:98290",
          "UMLS:C5681530",
          "icd11.foundation:1678636940"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 2,
      "reference_id": "MONDO:0020083"
    }
  ],
  "roots": [
    {
      "id": 4440,
      "label": "hematopoietic and lymphoid system neoplasm"
    }
  ]
}