{
  "id": 16596,
  "label": "mixed germ cell tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0015864",
  "properties": {
    "xrefs": [
      "DOID:3306",
      "GARD:0020202",
      "ICDO:9085/3",
      "MEDGEN:87257",
      "NANDO:2200071",
      "NCIT:C4290",
      "Orphanet:180234",
      "UMLS:C0334524"
    ],
    "synonyms": [
      "combined germ cell neoplasm",
      "combined germ cell tumor",
      "combined germ cell tumour",
      "mixed germ cell cancer",
      "mixed germ cell neoplasm",
      "mixed germ cell tumor"
    ],
    "definition": "A malignant germ cell tumor characterized by the presence of at least two different germ cell components. The different germ cell components include choriocarcinoma, embryonal carcinoma, yolk sac tumor, teratoma, and seminoma. It occurs in the ovary, testis, and extragonadal sites including central nervous system and mediastinum."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 7832,
      "label": "malignant germ cell tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        6773
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000352",
          "GARD:0003360",
          "MEDGEN:890580",
          "NCIT:C4925",
          "SCTID:145831000119103",
          "UMLS:C4048549"
        ],
        "synonyms": [
          "cancer of germ cell",
          "germ cell cancer",
          "germ cell tumor, malignant",
          "malignant germ cell neoplasm",
          "malignant germ cell tumor",
          "malignant neoplasm of germ cell",
          "malignant neoplasm of the germ cell",
          "malignant tumor of germ cell",
          "malignant tumor of the germ cell",
          "malignant tumour of germ cell",
          "malignant tumour of the germ cell"
        ],
        "definition": "A gonadal or extragonadal malignant neoplasm that arises from germ cells. Representative examples include embryonal carcinoma, yolk sac tumor, and seminoma."
      },
      "child_count": 26,
      "reference_id": "MONDO:0006290"
    }
  ],
  "children": [
    {
      "id": 2973,
      "label": "mixed extragonadal germ cell cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5094,
        16596
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050907",
          "GARD:0022790"
        ],
        "definition": "A mixed germ cell cancer that is located in areas of the body other than the ovary or testicle."
      },
      "child_count": 2,
      "reference_id": "MONDO:0000524"
    },
    {
      "id": 4655,
      "label": "teratocarcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16596
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3305",
          "GARD:0023183",
          "ICDO:9081/3",
          "MEDGEN:104913",
          "MESH:D018243",
          "NCIT:C3756",
          "UMLS:C0206664"
        ],
        "synonyms": [
          "mixed embryonal carcinoma and teratoma",
          "teratocarcinoma",
          "teratocarcinoma (morphologic abnormality)"
        ],
        "definition": "A germ cell tumor characterized by the presence of an embryonal carcinoma component and a teratoma component."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002599"
    },
    {
      "id": 5098,
      "label": "mixed testicular germ cell cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5424,
        16596
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4743",
          "GARD:0023372",
          "MEDGEN:237005",
          "NCIT:C6347",
          "ONCOTREE:MGCT",
          "UMLS:C1336720"
        ],
        "synonyms": [
          "mixed germ cell neoplasm of testis",
          "mixed germ cell neoplasm of the testis",
          "mixed germ cell tumor",
          "mixed germ cell tumor of testis",
          "mixed germ cell tumor of the testis",
          "mixed germ cell tumour",
          "mixed germ cell tumour of testis",
          "mixed germ cell tumour of the testis",
          "mixed testicular germ cell tumor",
          "mixed testicular germ cell tumour",
          "testicular germ cell tumor (mixed)",
          "testicular germ cell tumour (mixed)",
          "testicular mixed germ cell neoplasm",
          "testicular mixed germ cell tumor",
          "testicular mixed germ cell tumour",
          "testis mixed germ cell tumor",
          "testis mixed germ cell tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A malignant germ cell tumor that arises from the testis and is characterized by the presence of more than one histologic component. Representative examples include mixed choriocarcinoma and embryonal carcinoma, mixed embryonal carcinoma and seminoma, and mixed yolk sac tumor and teratoma."
      },
      "child_count": 2,
      "reference_id": "MONDO:0003120"
    },
    {
      "id": 5592,
      "label": "ovarian mixed germ cell neoplasm",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5339,
        16596
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5936",
          "GARD:0023629",
          "MEDGEN:83602",
          "NCIT:C8114",
          "ONCOTREE:OMGCT",
          "UMLS:C0280135"
        ],
        "synonyms": [
          "mixed germ cell neoplasm of ovary",
          "mixed germ cell neoplasm of the ovary",
          "mixed germ cell tumor of ovary",
          "mixed germ cell tumor of the ovary",
          "mixed germ cell tumour of ovary",
          "mixed germ cell tumour of the ovary",
          "ovarian mixed germ cell neoplasm",
          "ovarian mixed germ cell tumor",
          "ovarian mixed germ cell tumour",
          "ovary mixed germ cell tumor",
          "ovary mixed germ cell tumour",
          "mixed germ cell tumor",
          "mixed germ cell tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An ovarian malignant germ cell tumor characterized by the presence of at least two different germ cell components. At least one of the germ cell components is primitive. The most common combination of germ cell elements is dysgerminoma and yolk sac tumor."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003710"
    },
    {
      "id": 20065,
      "label": "mixed germ cell tumor of vulva",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3735,
        16596,
        20064
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ONCOTREE:VMGCT"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0020651"
    },
    {
      "id": 21595,
      "label": "mixed teratoma and seminoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16596
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025466",
          "MEDGEN:1844722",
          "NCIT:C9010",
          "UMLS:C5848073"
        ],
        "synonyms": [
          "mixed teratoma and seminoma"
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0024861"
    }
  ],
  "roots": [
    {
      "id": 7832,
      "label": "malignant germ cell tumor"
    }
  ]
}