{
  "id": 16653,
  "label": "fetal alcohol syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016011",
  "properties": {
    "xrefs": [
      "DOID:0050665",
      "DOID:0050667",
      "ICD10CM:Q86.0",
      "MEDGEN:8820",
      "MedDRA:10016845",
      "NCIT:C84713",
      "Orphanet:1915",
      "SCTID:205788004",
      "UMLS:C0015923",
      "icd11.foundation:362980699"
    ],
    "synonyms": [
      "FASD",
      "fetal alcohol spectrum disorders",
      "foetal alcohol spectrum disorders",
      "ARBD",
      "ARND",
      "FAS",
      "alcohol-related neurodevelopmental disorder",
      "alcohol-related birth defects",
      "static encephalopathy"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Fetal alcohol syndrome (FAS) is a rare malformation syndrome caused by excessive maternal consumption of alcohol during pregnancy. It is characterized by prenatal and/or postnatal growth deficiency (weight and/or height <10th percentile), a unique cluster of minor facial anomalies (short palpebral fissures, flat and smooth philtrum, and thin upper lip) and severe central nervous system (CNS) abnormalities including microcephaly, and cognitive and behavioral impairment (intellectual disability, deficit in general cognition, learning and language, executive function, visual-spatial processing, memory, and attention)."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 2897,
      "label": "fetal alcohol spectrum disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3008,
        4432,
        20730
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050696",
          "MEDGEN:457516",
          "MESH:D063647",
          "NCIT:C92780",
          "SCTID:609437000",
          "UMLS:C2985290"
        ],
        "synonyms": [
          "fetal alcohol spectrum disorders",
          "foetal alcohol spectrum disorders",
          "FAE (fetal alcohol effects)",
          "FAEs (fetal alcohol effects)",
          "FASD",
          "FASDs",
          "alcohol related birth defects",
          "alcohol related neurodevelopmental disorder",
          "alcohol-related birth defects",
          "alcohol-related birth defects (ARBD) - type",
          "alcohol-related neurodevelopmental disorder (ARND) - type",
          "birth defects, alcohol-related",
          "fetal alcohol syndrome",
          "fetal alcohol syndrome (FAS) - type",
          "foetal alcohol syndrome",
          "foetal alcohol syndrome (FAS) - type",
          "growth retardation, facial abnormalities, and central nervous system dysfunction",
          "partial fetal alcohol syndrome",
          "partial foetal alcohol syndrome",
          "syndrome, fetal alcohol",
          "syndrome, foetal alcohol"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A group of disorders caused by a prenatal exposure to maternal consumption of alcohol leading to a range of behavioral, cognitive and neurological deficits in the offspring. It is characterized by physical growth problems, distinct facies, and varying psycho-neurological issues."
      },
      "child_count": 12,
      "reference_id": "MONDO:0000408"
    },
    {
      "id": 4370,
      "label": "syndromic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:225",
          "MEDGEN:11688",
          "MESH:D013577",
          "NCIT:C28193",
          "OGMS:0000086",
          "UMLS:C0039082"
        ],
        "synonyms": [
          "cluster, symptom",
          "clusters, symptom",
          "symptom cluster",
          "symptom clusters",
          "syndrome",
          "syndrome associated with disease or disorder",
          "syndromes",
          "syndromic disease",
          "syndromic disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition."
      },
      "child_count": 1182,
      "reference_id": "MONDO:0002254"
    },
    {
      "id": 17143,
      "label": "toxic or drug-related embryofetopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19507
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1843068",
          "MESH:D000014",
          "Orphanet:251529",
          "UMLS:C5680710",
          "icd11.foundation:293076727"
        ],
        "definition": "Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment."
      },
      "child_count": 22,
      "reference_id": "MONDO:0016677"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 2897,
      "label": "fetal alcohol spectrum disorder"
    },
    {
      "id": 4370,
      "label": "syndromic disease"
    },
    {
      "id": 17143,
      "label": "toxic or drug-related embryofetopathy"
    }
  ]
}