{
  "id": 16673,
  "label": "superficial Fibromatosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016037",
  "properties": {
    "xrefs": [
      "EFO:1000556",
      "ICD9:729.99",
      "MEDGEN:140804",
      "NCIT:C6814",
      "Orphanet:199257",
      "SCTID:238853007",
      "UMLS:C0406571"
    ],
    "synonyms": [
      "superficial Fibromatosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "A poorly circumscribed, intermediate fibrocytic neoplasm arising from the superficial soft tissues. It is characterized by the presence of spindle-shaped fibroblasts, and an infiltrative growth pattern."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 6765,
      "label": "fibromatosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7762
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0000497",
          "MEDGEN:8836",
          "NCIT:C3042",
          "SCTID:723976005",
          "UMLS:C0016048"
        ],
        "synonyms": [
          "fibromatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A poorly circumscribed neoplasm arising from the soft tissues. It is characterized by the presence of spindle-shaped fibroblasts and an infiltrative growth pattern."
      },
      "child_count": 3,
      "reference_id": "MONDO:0005031"
    }
  ],
  "children": [
    {
      "id": 6466,
      "label": "plantar fibromatosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16673
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8936",
          "EFO:1000481",
          "GARD:0006873",
          "ICD9:728.71",
          "MEDGEN:56385",
          "MESH:C537000",
          "MedDRA:10035154",
          "NCIT:C4680",
          "Orphanet:199251",
          "SCTID:13370002",
          "UMLS:C0158360",
          "icd11.foundation:409482033"
        ],
        "synonyms": [
          "Ledderhose's disease",
          "Lederhose disease",
          "plantar fibromatosis",
          "plantar part of pes superficial Fibromatosis",
          "plantar part of pes superficial fibromatosis",
          "superficial fibromatosis of plantar part of pes",
          "plantar fascial fibromatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A superficial fibromatosis arising from soft tissue of the plantar regions. It is characterized by the presence of spindle-shaped fibroblasts, hypercellularity, and an infiltrative growth pattern."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004684"
    },
    {
      "id": 7871,
      "label": "palmar fibromatosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16673
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000438",
          "HP:0005679",
          "MEDGEN:903450",
          "MESH:D004387",
          "NCIT:C3469",
          "SCTID:203045001",
          "UMLS:C4085370",
          "icd11.foundation:160345690"
        ],
        "synonyms": [
          "Dupuytren contracture",
          "Dupuytren contracture (disease)",
          "palmar fibromatosis",
          "palmar part of manus fibromatosis",
          "Dupuytren's contracture"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A superficial fibromatosis arising from the soft tissue of the palm. It is characterized by the presence of spindle-shaped fibroblasts, and an infiltrative growth pattern. It predominantly affects adult males."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006345"
    },
    {
      "id": 8863,
      "label": "familial Dupuytren contracture",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4599,
        16673
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:41672",
          "OMIM:126900",
          "Orphanet:79142",
          "SCTID:274142002",
          "UMLS:C0013312"
        ],
        "synonyms": [
          "Dupuytren contracture",
          "Dupuytren contracture 1",
          "plantar fibromas",
          "plantar fibromatosis, familial"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "Familial Dupuyren contracture is a rare, genetic, epidermal disease characterized by a, usually unilateral, progressive thickening and shortening of the palmar fascia, leading to permanent flexion contracture of the digits in several members of a family. It most commonly affects the fourth digit, followed by the fifth and then the third (first and second digits are usually spared)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007476"
    },
    {
      "id": 9538,
      "label": "Peyronie disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8333,
        16673,
        21247
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8616",
          "ICD10CM:N48.6",
          "ICD9:607.85",
          "MEDGEN:10629",
          "NCIT:C3316",
          "OMIM:171000",
          "Orphanet:2870",
          "UMLS:C0030848"
        ],
        "synonyms": [
          "Peyronie disease",
          "Peyronie's disease",
          "Peyronie's fibromatosis",
          "penile fibromatosis",
          "penile induration",
          "penis fibromatosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A condition characterized by hardening of the penis due to the formation of fibrous plaques on the dorsolateral aspect of the penis, usually involving the membrane (tunica albuginea) surrounding the erectile tissue (corpus cavernosum penis). This may eventually cause a painful deformity of the shaft or constriction of the urethra, or both."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008231"
    },
    {
      "id": 16674,
      "label": "calcified aponeurotic fibroma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6889,
        16673
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020329",
          "MEDGEN:107818",
          "NCIT:C4818",
          "Orphanet:199260",
          "SCTID:703614006",
          "UMLS:C0553647"
        ],
        "synonyms": [
          "Juvenile aponeurotic fibroma",
          "Juvenile aponeurotic fibrosis",
          "Keasby tumor",
          "Keasby tumour",
          "juvenile aponeurotic fibromatosis",
          "calcifying aponeurotic fibroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A rare slow-growing benign neoplasm arising from the soft tissues in children. It is a poorly circumscribed tumor characterized by the presence of chondrocyte-like cells, nodular calcification, nuclear palisading, and in some cases osteoclastic giant cells."
      },
      "child_count": 0,
      "reference_id": "MONDO:0016038"
    },
    {
      "id": 16675,
      "label": "infantile digital fibromatosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16673
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0008487",
          "HP:0025197",
          "ICD9:238.8",
          "MEDGEN:232929",
          "NCIT:C3456",
          "Orphanet:199267",
          "SCTID:399903008",
          "UMLS:C1318562",
          "icd11.foundation:246280296"
        ],
        "synonyms": [
          "Reye tumor",
          "Reye tumour",
          "Reye's tumor",
          "Reye's tumour",
          "digital fibrous tumor of Reye",
          "digital fibrous tumour of Reye",
          "inclusion body fibromatosis",
          "inclusion body fibromatosis (disease)",
          "infantile digital fibroma/fibromatosis",
          "infantile digital fibromatosis",
          "recurring digital fibrous tumor of childhood",
          "recurring digital fibrous tumour of childhood",
          "IDF",
          "asymptomatic nodular proliferation of fibrous tissue on the dorsal and lateral aspects of the fingers or toes"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0016039"
    }
  ],
  "roots": [
    {
      "id": 6765,
      "label": "fibromatosis"
    }
  ]
}