{
  "id": 16679,
  "label": "isolated cleft lip",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016043",
  "properties": {
    "xrefs": [
      "GARD:0017091",
      "MEDGEN:40327",
      "MedDRA:10009259",
      "Orphanet:199302",
      "UMLS:C0008924",
      "icd11.foundation:172183323"
    ],
    "synonyms": [
      "isolated cleft lip (disease)",
      "nonsyndromic cleft lip (disease)"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "Isolated cleft lip is a fissure type embryopathy extending from the upper lip to the nasal base."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6518,
      "label": "cleft lip",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2863
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9296",
          "HP:0410030",
          "ICD10CM:Q36",
          "ICD10WHO:Q36",
          "ICD9:749.1",
          "ICD9:749.10",
          "ICD9:749.11",
          "MEDGEN:1370297",
          "MESH:D002971",
          "NCIT:C87175",
          "SCTID:80281008",
          "UMLS:C4321245"
        ],
        "synonyms": [
          "cheiloschisis",
          "cleft lip",
          "cleft lip (disease)",
          "cleft lip, unilateral, complete",
          "labium leporinum"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A congenital abnormality consisting of one or more clefts (splits) in the upper lip, which may be accompanied by a cleft palate; it is the result of the failure of the embryonic parts of the lip to fuse."
      },
      "child_count": 3,
      "reference_id": "MONDO:0004747"
    },
    {
      "id": 20383,
      "label": "disorder of development or morphogenesis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:Q00-Q99",
          "MEDGEN:1843482",
          "UMLS:C0694457"
        ],
        "definition": "Any disease or disorder that disrupts the process development of an anatomical structure. Can be due to genetic or environmental causes. Typically happens during embryogenesis, but also includes post-embryonic development."
      },
      "child_count": 190,
      "reference_id": "MONDO:0021147"
    }
  ],
  "children": [
    {
      "id": 12060,
      "label": "orofacial cleft 3",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8731,
        16679
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080397",
          "GARD:0024761",
          "MEDGEN:318860",
          "MESH:C563448",
          "OMIM:600757",
          "UMLS:C1833369"
        ],
        "synonyms": [
          "OFC3",
          "orofacial cleft 3",
          "cleft lip with or without cleft palate, nonsyndromic, 3"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0010927"
    },
    {
      "id": 13206,
      "label": "orofacial cleft 5",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16269,
        16679,
        16680
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080399",
          "GARD:0018305",
          "MEDGEN:373280",
          "MESH:C563843",
          "OMIM:608874",
          "UMLS:C1837210"
        ],
        "synonyms": [
          "MSX1 orofacial cleft",
          "orofacial cleft 5",
          "orofacial cleft caused by mutation in MSX1",
          "orofacial cleft type 5",
          "OFC5",
          "cleft lip with or without cleft palate, nonsyndromic, 5"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Any orofacial cleft in which the cause of the disease is a mutation in the MSX1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012142"
    }
  ],
  "roots": [
    {
      "id": 6518,
      "label": "cleft lip"
    },
    {
      "id": 20383,
      "label": "disorder of development or morphogenesis"
    }
  ]
}