{
  "id": 16693,
  "label": "laryngotracheoesophageal cleft",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016060",
  "properties": {
    "xrefs": [
      "GARD:0003188",
      "MESH:C537875",
      "NCIT:C98622",
      "Orphanet:2004",
      "SCTID:232461002",
      "icd11.foundation:271795917"
    ],
    "synonyms": [
      "LC",
      "LTEC",
      "Larnygeotracheoesophageal cleft",
      "congenital cleft larynx",
      "laryngeal cleft",
      "laryngo-tracheo-esophageal cleft",
      "laryngo-tracheo-esophageal diastema",
      "tracheal cleft"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "A laryngo-tracheo-esophageal cleft (LC) is a congenital malformation characterized by an abnormal, posterior, sagittal communication between the larynx and the pharynx, possibly extending downward between the trachea and the esophagus."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 4630,
      "label": "tracheal disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2809,
        6623
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3225",
          "MEDGEN:892789",
          "MESH:D014133",
          "NCIT:C35079",
          "SCTID:47125007",
          "UMLS:C4025678"
        ],
        "synonyms": [
          "disease of trachea",
          "disease or disorder of trachea",
          "disorder of trachea",
          "trachea disease",
          "trachea disease or disorder",
          "tracheal disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the trachea. Representative examples of non-neoplastic disorders include congenital malformations and infection. Representative examples of neoplastic disorders include carcinoma and lymphoma."
      },
      "child_count": 16,
      "reference_id": "MONDO:0002567"
    },
    {
      "id": 5629,
      "label": "esophageal disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23495
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6050",
          "EFO:0009544",
          "ICD9:530",
          "ICD9:530.2",
          "ICD9:530.20",
          "ICD9:530.9",
          "MEDGEN:8693",
          "MESH:D004935",
          "NCIT:C3027",
          "SCTID:30811009",
          "SCTID:37657006",
          "UMLS:C0014852",
          "icd11.foundation:1594312948"
        ],
        "synonyms": [
          "disease of esophagus",
          "disease of oesophagus",
          "disease or disorder of esophagus",
          "disease or disorder of oesophagus",
          "disorder of esophagus",
          "disorder of oesophagus",
          "esophageal disorder",
          "esophagus disease",
          "esophagus disease or disorder",
          "oesophagus disease",
          "oesophagus disease or disorder",
          "esophageal ulcer"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas."
      },
      "child_count": 20,
      "reference_id": "MONDO:0003749"
    }
  ],
  "children": [
    {
      "id": 10247,
      "label": "cleft larynx, posterior",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16693
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0004015",
          "MEDGEN:349091",
          "MESH:C537851",
          "OMIM:215800",
          "Orphanet:2005",
          "UMLS:C1859083"
        ],
        "synonyms": [
          "cleft larynx, posterior",
          "Novak syndrome",
          "laryngotracheoesophageal cleft pulmonary hypoplasia",
          "stridor, congenital"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0008990"
    },
    {
      "id": 17559,
      "label": "laryngotracheoesophageal cleft type 0",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16693
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021072",
          "MEDGEN:1760178",
          "Orphanet:280205",
          "UMLS:C5438977"
        ],
        "synonyms": [
          "LTEC0",
          "laryngo-tracheo-esophageal cleft type 0"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Laryngo-tracheo-esophageal cleft (LC) type 0 is a congenital respiratory tract anomaly characterized by a submucosal laryngo-tracheo-esophageal cleft with minor symptoms or an asymptomatic course."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017220"
    },
    {
      "id": 19512,
      "label": "laryngotracheoesophageal cleft type 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16693
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019236",
          "MEDGEN:667239",
          "Orphanet:93938",
          "UMLS:C0584823"
        ],
        "synonyms": [
          "LTEC I",
          "LTEC1",
          "laryngo-tracheo-esophageal cleft type 1"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Laryngo-tracheo-esophageal cleft (LC) type 1 is a congenital respiratory tract anomaly characterized by a supraglottic, interarytenoid cleft above the vocal folds with moderate respiratory symptoms."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019761"
    },
    {
      "id": 19513,
      "label": "laryngotracheoesophageal cleft type 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16693
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019237",
          "MEDGEN:667240",
          "Orphanet:93939",
          "UMLS:C0584824"
        ],
        "synonyms": [
          "LTEC II",
          "LTEC2",
          "laryngo-tracheo-esophageal cleft type 2"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Laryngo-tracheo-esophageal cleft (LC) type 2 is a congenital respiratory tract anomaly characterized by a cleft extending below the vocal folds into the cricoid cartilage, with swallowing disorders and lung infections."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019762"
    },
    {
      "id": 19514,
      "label": "laryngotracheoesophageal cleft type 3",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16693
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016833",
          "MEDGEN:667241",
          "Orphanet:93940",
          "UMLS:C0584825"
        ],
        "synonyms": [
          "LTEC III",
          "LTEC3",
          "laryngo-tracheo-esophageal cleft type 3"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Laryngo-tracheo-esophageal cleft (LC) type 3 is a congenital respiratory tract anomaly characterized by a cleft extending through the cricoid cartilage, sometimes into the cervical trachea, with severe swallowing disorders, lung infections and pulmonary damage."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019763"
    },
    {
      "id": 19515,
      "label": "laryngotracheoesophageal cleft type 4",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16693
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019238",
          "MEDGEN:667243",
          "Orphanet:93941",
          "UMLS:C0584827"
        ],
        "synonyms": [
          "LTEC IV",
          "LTEC4",
          "laryngo-tracheo-esophageal cleft type 4"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Laryngo-tracheo-esophageal cleft (LC) type 4 is a serious congenital respiratory tract anomaly characterized by a cleft extending into the thoracic trachea and possibly down to the carina, with respiratory distress."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019764"
    }
  ],
  "roots": [
    {
      "id": 4630,
      "label": "tracheal disorder"
    },
    {
      "id": 5629,
      "label": "esophageal disorder"
    }
  ]
}