{
  "id": 16697,
  "label": "cleft palate",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016064",
  "properties": {
    "xrefs": [
      "DOID:674",
      "ICD10CM:Q35",
      "ICD10WHO:Q35",
      "ICD9:749.0",
      "ICD9:749.00",
      "MEDGEN:756015",
      "MESH:D002972",
      "MedDRA:10009269",
      "NCIT:C87069",
      "Orphanet:2014",
      "SCTID:63567004",
      "UMLS:C2981150",
      "icd11.foundation:2129534948"
    ],
    "synonyms": [
      "palatoschisis",
      "uranostaphyloschisis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "Cleft palate is a fissure type embryopathy that affects the soft and hard palate to varying degrees."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 9,
  "parents": [
    {
      "id": 2863,
      "label": "orofacial cleft",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        21213
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050567",
          "MEDGEN:472000",
          "OMIMPS:119530",
          "SCTID:449790007",
          "UMLS:C3266076"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A disorder of facial skeleton that is characterized by cleft lip and/or cleft palate that result in feeding, speech and hearing problems caused by failures during development."
      },
      "child_count": 32,
      "reference_id": "MONDO:0000358"
    },
    {
      "id": 19507,
      "label": "developmental defect during embryogenesis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:759.7",
          "MEDGEN:1825997",
          "NCIT:C99267",
          "Orphanet:93890",
          "SCTID:400038003",
          "UMLS:C5680284"
        ],
        "synonyms": [
          "congenital malformation syndrome",
          "developmental defect during embryogenesis",
          "disorder of embryonic morphogenesis",
          "embryonic morphogenesis disease",
          "malformation syndrome",
          "rare developmental defect during embryogenesis"
        ],
        "definition": "A disease that has its basis in the disruption of embryonic morphogenesis."
      },
      "child_count": 52,
      "reference_id": "MONDO:0019755"
    }
  ],
  "children": [
    {
      "id": 8731,
      "label": "isolated cleft palate",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16697
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110213",
          "GARD:0001896",
          "MEDGEN:332392",
          "OMIM:119540",
          "UMLS:C1837218"
        ],
        "synonyms": [
          "isolated cleft palate",
          "nonsyndromic cleft palate",
          "CPI",
          "cleft palate",
          "cleft palate, isolated",
          "dominant cleft palate"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "A cleft palate that is not part of a larger syndrome."
      },
      "child_count": 1,
      "reference_id": "MONDO:0007336"
    },
    {
      "id": 8733,
      "label": "cleft soft palate",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16697
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110214",
          "GARD:0016907",
          "ICD10CM:Q35.3",
          "MEDGEN:98471",
          "MESH:C562950",
          "OMIM:119570",
          "Orphanet:99772",
          "SCTID:253997002",
          "UMLS:C0432098",
          "icd11.foundation:797497023"
        ],
        "synonyms": [
          "cleft soft palate",
          "cleft velum",
          "cleft velum palatinum"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Cleft velum is a fissure type embryopathy that affects in varying degrees the soft palate."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007338"
    },
    {
      "id": 8891,
      "label": "Rapp-Hodgkin syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2903,
        6518,
        16697,
        19138,
        29233
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060330",
          "GARD:0005690",
          "MEDGEN:315656",
          "MESH:C535289",
          "OMIM:129400",
          "Orphanet:3022",
          "SCTID:7731005",
          "UMLS:C1785148",
          "icd11.foundation:1455333054"
        ],
        "synonyms": [
          "Rapp-Hodgkin syndrome",
          "OFC8, included",
          "RHS",
          "Rapp-Hodgkin ectodermal dysplasia syndrome",
          "cleft lip with or without cleft palate, nonsyndromic, 8",
          "ectodermal dysplasia, anhidrotic, with cleft Lip/palate",
          "ectodermal dysplasia, anhidrotic, with cleft lip-palate",
          "orofacial cleft 8"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A form of ectodermal dysplasia characterized by the association of anhidrotic ectodermal dysplasia with cleft lip/palate."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007508"
    },
    {
      "id": 9919,
      "label": "bifid uvula",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16697
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019687",
          "MEDGEN:1646931",
          "OMIM:192100",
          "Orphanet:99771",
          "SCTID:18910001",
          "UMLS:C4551488",
          "icd11.foundation:684398038"
        ],
        "synonyms": [
          "bifidity of the uvula",
          "uvular cleft",
          "uvula, bifid",
          "uvula, cleft"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Bifid uvula is a fissure type embryopathy affecting the uvula at the back of the soft palate."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008637"
    },
    {
      "id": 11714,
      "label": "cleft palate with or without ankyloglossia, X-linked",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16697
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060613",
          "GARD:0001394",
          "MEDGEN:375520",
          "MESH:C536426",
          "OMIM:303400",
          "Orphanet:324601",
          "SCTID:766761000",
          "UMLS:C1844830"
        ],
        "synonyms": [
          "X-linked cleft palate and ankyloglossia",
          "cleft palate with ankyloglossia",
          "cleft palate with or without ankyloglossia, X-linked",
          "CPX",
          "X-linked cleft palate",
          "cleft palate X-linked",
          "cleft palate, X-linked"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "X-linked cleft palate and ankyloglossia is a rare, genetic developmental defect during embryogenesis syndrome characterized by the association of complete, partial or submucous cleft palate and ankyloglossia. Patients may also present abnormal uvula (e.g. absent, bifid, shortened or laterally deviated), short lingual frenulum and dental anomalies (e.g. buccal crossbite, absent and/or misshapen teeth). Digital abnormalities, such as mild clinodactyly and/or syndactyly, have also been reported."
      },
      "child_count": 0,
      "reference_id": "MONDO:0010560"
    },
    {
      "id": 16058,
      "label": "cleft hard palate",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16697
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019774",
          "ICD10CM:Q35.1",
          "MEDGEN:609341",
          "Orphanet:101023",
          "SCTID:448915004",
          "UMLS:C0432090",
          "icd11.foundation:1047415764"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0015092"
    },
    {
      "id": 16316,
      "label": "submucosal cleft palate",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16697
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019976",
          "MEDGEN:98472",
          "Orphanet:155878",
          "UMLS:C0432103",
          "icd11.foundation:1848627578"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0015479"
    },
    {
      "id": 21242,
      "label": "Kuster syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        6518,
        16697
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0003152",
          "MEDGEN:419150",
          "MESH:C538126",
          "UMLS:C2931741"
        ],
        "synonyms": [
          "cleft lip and palate, lower lip pits, and limb deficiency defects",
          "cleft lip palate lip pits limb deficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0023581"
    },
    {
      "id": 26041,
      "label": "soft and hard cleft palate",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16697
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027173",
          "Orphanet:664372"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0971092"
    }
  ],
  "roots": [
    {
      "id": 2863,
      "label": "orofacial cleft"
    },
    {
      "id": 19507,
      "label": "developmental defect during embryogenesis"
    }
  ]
}