{
  "id": 16798,
  "label": "spastic quadriplegic cerebral palsy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016215",
  "properties": {
    "xrefs": [
      "DOID:10970",
      "GARD:0017109",
      "ICD10CM:G80.0",
      "ICD9:343.2",
      "ICD9:344.09",
      "MEDGEN:98433",
      "NCIT:C116904",
      "OMIMPS:603513",
      "OMIMPS:612900",
      "Orphanet:210141",
      "SCTID:192965001",
      "UMLS:C0426970",
      "icd11.foundation:1155284708"
    ],
    "synonyms": [
      "inherited congenital spastic quadriplegia",
      "quadriplegic infantile cerebral palsy",
      "spastic quadriplegia",
      "spastic quadriplegic cerebral palsy",
      "spastic tetraplegia cerebral palsy",
      "tetraplegic infantile cerebral palsy",
      "inherited congenital spastic tetraplegia"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A type of spastic cerebral palsy characterized by increased muscle tone of all four extremities."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 2891,
      "label": "spastic cerebral palsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7991
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050669",
          "ICD9:344.89",
          "MEDGEN:137905",
          "NCIT:C116903",
          "SCTID:230773005",
          "UMLS:C0338596",
          "icd11.foundation:1426032265"
        ],
        "synonyms": [
          "hypertonic cerebral palsy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A form of cerebral palsy wherein spasticity is the exclusive impairment present."
      },
      "child_count": 5,
      "reference_id": "MONDO:0000396"
    },
    {
      "id": 24270,
      "label": "hereditary neurological disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6799
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "neurogenetic disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A heterogeneous group of genetic conditions with Mendelian (autosomal dominant, recessive, or X-linked) or chromosomal etiology characterized by abnormalities in the brain, spinal cord, nerves, or muscles."
      },
      "child_count": 528,
      "reference_id": "MONDO:0100545"
    }
  ],
  "children": [
    {
      "id": 14071,
      "label": "cerebral palsy, spastic quadriplegic, 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16798,
        24226
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081360",
          "GARD:0018309",
          "MEDGEN:442880",
          "MESH:C567867",
          "OMIM:612900",
          "UMLS:C2752061"
        ],
        "synonyms": [
          "KANK1 spastic quadriplegia",
          "cerebral palsy, spastic quadriplegic, 2",
          "cerebral palsy, spastic quadriplegic, type 2",
          "spastic quadriplegia caused by mutation in KANK1",
          "CPSQ2"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Any spastic quadriplegia in which the cause of the disease is a mutation in the KANK1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013033"
    },
    {
      "id": 15844,
      "label": "cerebral palsy, spastic quadriplegic, 3",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16798,
        24226,
        24241
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081361",
          "GARD:0018310",
          "MEDGEN:934734",
          "OMIM:617008",
          "UMLS:C4310767"
        ],
        "synonyms": [
          "ADD3 spastic quadriplegia",
          "CPSQ3",
          "cerebral palsy, spastic quadriplegic, 3",
          "cerebral palsy, spastic quadriplegic, 3; CPSQ3",
          "cerebral palsy, spastic quadriplegic, type 3",
          "spastic quadriplegia caused by mutation in ADD3"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Any spastic quadriplegia in which the cause of the disease is a mutation in the ADD3 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014862"
    },
    {
      "id": 22696,
      "label": "neurodevelopmental disorder with progressive spasticity and brain white matter abnormalities",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16798,
        24226
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010447",
          "MEDGEN:1736667",
          "MESH:C567853",
          "OMIM:603513",
          "OMIM:619026",
          "Orphanet:641353",
          "UMLS:C5436628"
        ],
        "synonyms": [
          "NEDSWMA",
          "cerebral palsy, spastic quadriplegic, 1",
          "cerebral palsy, spastic quadriplegic, type 1",
          "infantile neurodegeneration-progressive spasticity-intellectual disability-white matter lesions syndrome",
          "CPSQ1",
          "cerebral palsy spastic quadriplegic"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0033613"
    }
  ],
  "roots": [
    {
      "id": 2891,
      "label": "spastic cerebral palsy"
    },
    {
      "id": 24270,
      "label": "hereditary neurological disease"
    }
  ]
}