{
  "id": 16812,
  "label": "solitary fibrous tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016238",
  "properties": {
    "xrefs": [
      "GARD:0015014",
      "ICD9:238.1",
      "ICDO:8815/0",
      "ICDO:8815/1",
      "ICDO:9051/0",
      "MEDGEN:224764",
      "MESH:D054364",
      "MedDRA:10018825",
      "NCIT:C7634",
      "ONCOTREE:SFT",
      "Orphanet:2126",
      "UMLS:C1266119"
    ],
    "synonyms": [
      "SFT",
      "localised fibrous mesothelioma",
      "localised fibrous tumour",
      "localized fibrous mesothelioma",
      "localized fibrous tumor",
      "solitary fibrous tumor",
      "submesothelial fibroma",
      "hemangiopericytoma",
      "solitary fibrous tumor/hemangiopericytoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      }
    ],
    "definition": "Solitary fibrous tumor (SFT) represents a diverse group of ubiquitous rare spindle cell neoplasms that may be benign or malignant and that most frequently arises from the pleura and peritoneum and rarely from other sites such as head and neck, liver and skeletal muscle. SFT may be clinically asymptomatic or may present with enlarging mass, compressive effects depending on the site involved and rarely with paraneoplastic manifestations (osteoarthropathy or hypoglycemia)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 7762,
      "label": "fibroblastic neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4667,
        20678
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000255",
          "MEDGEN:60198",
          "NCIT:C7075",
          "UMLS:C0206643"
        ],
        "synonyms": [
          "fibroblastic neoplasm",
          "fibroblastic tumor",
          "fibroblastic tumour",
          "fibrocytic neoplasm",
          "fibrocytic tumor",
          "fibrocytic tumour",
          "fibrogenic neoplasm",
          "fibrogenicTumor",
          "fibrous neoplasm",
          "fibrous tumor",
          "fibrous tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A benign, intermediate, or malignant mesenchymal neoplasm characterized by the presence of neoplastic fibroblasts."
      },
      "child_count": 14,
      "reference_id": "MONDO:0006209"
    }
  ],
  "children": [
    {
      "id": 6484,
      "label": "liver solitary fibrous tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6889,
        16812,
        21432
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:907",
          "GARD:0024092",
          "MEDGEN:232273",
          "NCIT:C5752",
          "UMLS:C1333965"
        ],
        "synonyms": [
          "fibroma of liver",
          "fibroma of the liver",
          "hepatic fibroma",
          "liver fibroma",
          "liver localised fibrous mesothelioma",
          "liver localised fibrous tumour",
          "liver localized fibrous mesothelioma",
          "liver localized fibrous tumor",
          "liver solitary fibrous tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A solitary fibrous tumor that arises from the liver. It affects females more frequently than males. Signs and symptoms include the presence of an abdominal mass and abdominal discomfort."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004705"
    },
    {
      "id": 7735,
      "label": "dedifferentiated solitary fibrous tumor",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16812
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000214",
          "GARD:0024320",
          "MEDGEN:396654",
          "NCIT:C79948",
          "UMLS:C2699572"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A solitary fibrous tumor characterized by the presence of areas of abrupt transition to high grade sarcoma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006178"
    },
    {
      "id": 10562,
      "label": "hemangiopericytoma, malignant",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6821,
        16812
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0002627",
          "ICDO:9150/3",
          "MEDGEN:90803",
          "MESH:C562740",
          "NCIT:C4301",
          "OMIM:234820",
          "UMLS:C0334542"
        ],
        "synonyms": [
          "hemangiopericytoma, malignant",
          "malignant hemangiopericytoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "An uncommon malignant neoplasm arising from pericytes. Distinction between benign and malignant hemangiopericytoma may be difficult or even impossible on morphologic grounds alone."
      },
      "child_count": 8,
      "reference_id": "MONDO:0009330"
    },
    {
      "id": 20286,
      "label": "pleural solitary fibrous tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16812,
        20306
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025278",
          "NCIT:C4457",
          "SCTID:254646001"
        ],
        "synonyms": [
          "fibroma of pleura",
          "fibroma of the pleura",
          "localised fibrous mesothelioma of pleura",
          "localised fibrous mesothelioma of the pleura",
          "localized fibrous mesothelioma of pleura",
          "localized fibrous mesothelioma of the pleura",
          "pleura solitary fibrous tumor",
          "pleura solitary fibrous tumour",
          "pleural Submesothelial fibroma",
          "pleural cavity solitary fibrous tumor",
          "pleural cavity solitary fibrous tumour",
          "pleural fibroma",
          "pleural solitary fibrous tumor",
          "solitary fibrous tumor of pleura",
          "solitary fibrous tumor of the pleura",
          "solitary fibrous tumour of pleura",
          "solitary fibrous tumour of the pleura"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A localized neoplasm of probable fibroblastic derivation, that arises from the pleura. It is characterized by the presence of round to spindle-shaped cells, hylanized stroma formation, thin-walled branching blood vessels, and thin bands of collagen."
      },
      "child_count": 2,
      "reference_id": "MONDO:0021041"
    },
    {
      "id": 22968,
      "label": "peritoneal solitary fibrous tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8339,
        16812
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025822",
          "MEDGEN:925935",
          "NCIT:C126357",
          "UMLS:C4288403"
        ],
        "synonyms": [
          "peritoneal solitary fibrous tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A rare, usually benign fibroblastic neoplasm that arises from the peritoneum. It is characterized by the presence of prominent hemangiopericytoma-like vessels."
      },
      "child_count": 2,
      "reference_id": "MONDO:0037737"
    }
  ],
  "roots": [
    {
      "id": 7762,
      "label": "fibroblastic neoplasm"
    }
  ]
}