{
  "id": 16826,
  "label": "leiomyosarcoma of the corpus uteri",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016262",
  "properties": {
    "xrefs": [
      "DOID:5289",
      "EFO:1001974",
      "GARD:0020477",
      "MEDGEN:83679",
      "NCIT:C6340",
      "NORD:1817",
      "ONCOTREE:ULMS",
      "Orphanet:213625",
      "SCTID:447389009",
      "UMLS:C0280631"
    ],
    "synonyms": [
      "Uterine Leiomyosarcoma",
      "body of uterus leiomyosarcoma",
      "corpus uteri leiomyosarcoma",
      "leiomyosarcoma - uterus",
      "leiomyosarcoma of body of uterus",
      "leiomyosarcoma of corpus uteri",
      "leiomyosarcoma of the body of uterus",
      "leiomyosarcoma of the corpus uteri",
      "leiomyosarcoma of the uterine body",
      "leiomyosarcoma of the uterine corpus",
      "leiomyosarcoma of the uterus",
      "leiomyosarcoma of uterine body",
      "leiomyosarcoma of uterine corpus",
      "leiomyosarcoma of uterus",
      "uterine body leiomyosarcoma",
      "uterine corpus leiomyosarcoma",
      "uterine leiomyosarcoma",
      "uterus leiomyosarcoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "An aggressive malignant smooth muscle neoplasm, arising from the uterine corpus. It is characterized by a proliferation of neoplastic spindle cells."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 6327,
      "label": "mixed endometrial stromal and smooth muscle tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7941,
        20461
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8302",
          "MEDGEN:269077",
          "NCIT:C40178",
          "NCIT:C40179",
          "UMLS:C1513364"
        ],
        "synonyms": [
          "Stromomyoma",
          "mixed endometrial stromal and smooth muscle neoplasm",
          "uterine corpus soft tissue neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A benign or malignant mesenchymal neoplasm of the uterine corpus. Representative examples include leiomyoma, leiomyosarcoma, and endometrial stromal sarcoma."
      },
      "child_count": 8,
      "reference_id": "MONDO:0004526"
    },
    {
      "id": 6788,
      "label": "leiomyosarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4931,
        17662,
        18239
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1967",
          "EFO:0000564",
          "GARD:0006880",
          "ICD9:171.9",
          "ICDO:8890/3",
          "MEDGEN:9711",
          "MESH:D007890",
          "MedDRA:10024189",
          "NANDO:2200064",
          "NCIT:C3158",
          "NORD:1356",
          "ONCOTREE:LMS",
          "Orphanet:64720",
          "SCTID:443719001",
          "UMLS:C0023269"
        ],
        "synonyms": [
          "Leiomyosarcomas",
          "leiomyosarcoma",
          "leiomyosarcoma (excluding uterine leiomyosarcoma)",
          "leiomyosarcoma - not uterine",
          "leiomyosarcoma, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "An uncommon, aggressive malignant smooth muscle neoplasm, usually occurring in post-menopausal women. It is characterized by a proliferation of neoplastic spindle cells. Morphologic variants include epithelioid, granular cell, inflammatory and myxoid leimyosarcomas."
      },
      "child_count": 93,
      "reference_id": "MONDO:0005058"
    },
    {
      "id": 6926,
      "label": "uterine corpus sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6816,
        7594
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5165",
          "EFO:0002914",
          "GARD:0020476",
          "MEDGEN:137837",
          "MedDRA:10039497",
          "NCIT:C6339",
          "ONCOTREE:USARC",
          "Orphanet:213620",
          "SCTID:254877001",
          "UMLS:C0338113"
        ],
        "synonyms": [
          "body of uterus sarcoma",
          "corpus uteri sarcoma",
          "sarcoma of body of uterus",
          "sarcoma of corpus uteri",
          "sarcoma of the body of uterus",
          "sarcoma of the corpus uteri",
          "sarcoma of the uterine body",
          "sarcoma of the uterine corpus",
          "sarcoma of uterine body",
          "sarcoma of uterine corpus",
          "sarcoma of uterus",
          "uterine body sarcoma",
          "uterus sarcoma",
          "sarcoma of the uterus",
          "uterine sarcoma",
          "uterine sarcoma/mesenchymal"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A malignant mesenchymal neoplasm arising from the wall of the uterine corpus (uterine body). The most representative examples are leiomyosarcoma and endometrial stromal sarcoma."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005210"
    }
  ],
  "children": [
    {
      "id": 5661,
      "label": "uterine corpus epithelioid leiomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5291,
        16826
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6139",
          "GARD:0023667",
          "MEDGEN:274363",
          "NCIT:C40174",
          "ONCOTREE:UELMS",
          "UMLS:C1519851"
        ],
        "synonyms": [
          "body of uterus epithelioid leiomyosarcoma",
          "epithelioid leiomyosarcoma of body of uterus",
          "uterine corpus epithelioid leiomyosarcoma",
          "uterine epithelioid leiomyosarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A morphologic variant of leiomyosarcoma arising from the uterine corpus. It is characterized by the presence of epithelioid round cells with eosinophilic to clear cytoplasm."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003782"
    },
    {
      "id": 5787,
      "label": "uterine corpus myxoid leiomyosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5294,
        16826
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6567",
          "GARD:0023741",
          "MEDGEN:311426",
          "NCIT:C40175",
          "ONCOTREE:UMLMS",
          "UMLS:C1519861"
        ],
        "synonyms": [
          "body of uterus myxoid leiomyosarcoma",
          "myxoid leiomyosarcoma of body of uterus",
          "uterine corpus myxoid leiomyosarcoma",
          "uterine myxoid leiomyosarcoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A morphologic variant of leiomyosarcoma arising from the uterus corpus. It is characterized by the presence of cellular pleomorphism, malignant cells with large nuclei, and a myxoid stroma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003928"
    }
  ],
  "roots": [
    {
      "id": 6327,
      "label": "mixed endometrial stromal and smooth muscle tumor"
    },
    {
      "id": 6788,
      "label": "leiomyosarcoma"
    },
    {
      "id": 6926,
      "label": "uterine corpus sarcoma"
    }
  ]
}