{
  "id": 16875,
  "label": "non-familial hypertrophic cardiomyopathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016330",
  "properties": {
    "xrefs": [
      "MEDGEN:1843178",
      "Orphanet:217598",
      "UMLS:C5680883"
    ],
    "synonyms": [
      "acquired hypertrophic cardiomyopathy"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "An instance of hypertrophic cardiomyopathy that is acquired during the lifetime of the individual."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 6777,
      "label": "hypertrophic cardiomyopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3007
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11984",
          "EFO:0000538",
          "HP:0001639",
          "ICD10CM:I42.1",
          "ICD10CM:I42.2",
          "ICD9:425.1",
          "ICD9:425.11",
          "ICD9:425.4",
          "MEDGEN:2881",
          "MESH:D002312",
          "MedDRA:10020871",
          "NANDO:1200286",
          "NANDO:1200288",
          "NANDO:2100054",
          "NANDO:2200229",
          "NANDO:2201042",
          "NCIT:C34449",
          "Orphanet:217569",
          "SCTID:233873004",
          "UMLS:C0007194",
          "icd11.foundation:1830681485"
        ],
        "synonyms": [
          "hypertrophic cardiomyopathy",
          "hypertrophic subaortic stenosis",
          "obstructive hypertrophic cardiomyopathy",
          "familial hypertrophic cardiomyopathy",
          "HCM - hypertrophic cardiomyopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A condition in which the myocardium is hypertrophied without an obvious cause. The hypertrophy is generally asymmetric and may be associated with obstruction of the ventricular outflow tract."
      },
      "child_count": 3,
      "reference_id": "MONDO:0005045"
    }
  ],
  "children": [
    {
      "id": 16877,
      "label": "hypertrophic cardiomyopathy due to intensive athletic training",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16875
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025071",
          "Orphanet:217601",
          "icd11.foundation:183927358"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0016332"
    },
    {
      "id": 18855,
      "label": "cirrhotic cardiomyopathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16875,
        16879
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018852",
          "MEDGEN:1391593",
          "Orphanet:57777",
          "SCTID:725416005",
          "UMLS:C4511053",
          "icd11.foundation:1268082489"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Cirrhotic cardiomyopathy is the term used to describe a constellation of features indicative of abnormal heart structure and function in patients with cirrhosis. These include systolic and diastolic dysfunction, electrophysiological changes, and macroscopic and microscopic structural changes."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018932"
    },
    {
      "id": 19265,
      "label": "AL amyloidosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6799,
        7996,
        16875,
        16883,
        18960
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080933",
          "GARD:0005797",
          "MEDGEN:75674",
          "MESH:C531616",
          "MedDRA:10036673",
          "NANDO:1200211",
          "NCIT:C158963",
          "Orphanet:85443",
          "UMLS:C0268381",
          "icd11.foundation:1061366491",
          "icd11.foundation:113043090"
        ],
        "synonyms": [
          "Light-chain amyloidosis",
          "primary amyloidosis",
          "Light chain amyloidosis",
          "amyloidosis AL",
          "amyloidosis primary systemic",
          "primary AL amyloidosis",
          "primary systemic AL amyloidosis",
          "primary systemic amyloidosis",
          "systemic AL amyloidsis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "AL Amyloidosis is a plasma cell disorder characterized by the aggregation and deposition of insoluble amyloid fibrils derived from misfolding of monoclonal immunoglobulin light chains usually produced by a plasma cell tumor. It usually presents as primary systemic amyloidosis (PSA) with multiple organ involvement and less frequently as primary localized amyloidosis (PLA) restricted to a single organ."
      },
      "child_count": 10,
      "reference_id": "MONDO:0019438"
    }
  ],
  "roots": [
    {
      "id": 6777,
      "label": "hypertrophic cardiomyopathy"
    }
  ]
}