{
  "id": 16893,
  "label": "limited systemic sclerosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016359",
  "properties": {
    "xrefs": [
      "GARD:0009749",
      "MEDGEN:220934",
      "NCIT:C116789",
      "Orphanet:220407",
      "SCTID:128461001",
      "UMLS:C1290138",
      "icd11.foundation:187455179"
    ],
    "synonyms": [
      "SSC without skin involvement",
      "systemic sclerosis sine scleroderma",
      "systemic sclerosis without skin involvement",
      "Scleroderma, sine",
      "progressive systemic sclerosis sine scleroderma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "Limited systemic sclerosis (lSSc) (or SSc sine scleroderma) is a subset of systemic sclerosis (SSc) characterized by organ involvement in the absence of fibrosis of the skin."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6827,
      "label": "systemic sclerosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6820,
        19180
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:418",
          "EFO:0000717",
          "GARD:0009748",
          "ICD10CM:M34",
          "ICD10WHO:M34",
          "ICD9:710.1",
          "MEDGEN:19897",
          "MESH:D012595",
          "MedDRA:10042953",
          "NANDO:1200277",
          "NANDO:2200429",
          "NCIT:C72070",
          "NORD:2007",
          "Orphanet:90291",
          "SCTID:89155008",
          "UMLS:C0036421",
          "icd11.foundation:1084365812"
        ],
        "synonyms": [
          "Scleroderma",
          "PSS (progressive systemic sclerosis)",
          "SSc",
          "SSc, diffuse sclerosis",
          "Scleroderma (& [systemic sclerosis])",
          "Scleroderma, diffuse",
          "Scleroderma, systemic",
          "Systemic Scleroderma",
          "diffuse Scleroderma",
          "diffuse sclerosis",
          "systemic Scleroderma",
          "systemic scleroderma",
          "systemic sclerosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. The two types of systemic scleroderma, limited cutaneous and diffuse cutaneous are classified with focus on the extent of affected skin. A relationship exists between the extent of skin area affected and degree of internal organ/system involvement. Systemic scleroderma can manifest itself in pulmonary fibrosis, Raynaud's syndrome, digestive system telangiectasias, renal hypertension and/or pulmonary hypertension."
      },
      "child_count": 12,
      "reference_id": "MONDO:0005100"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6827,
      "label": "systemic sclerosis"
    }
  ]
}