{
  "id": 16914,
  "label": "nephrogenic diabetes insipidus",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016383",
  "properties": {
    "xrefs": [
      "DOID:12387",
      "GARD:0007178",
      "ICD10CM:N25.1",
      "ICD9:588.1",
      "MEDGEN:57876",
      "MESH:D018500",
      "MedDRA:10029147",
      "NANDO:1200742",
      "NANDO:2200326",
      "NCIT:C84919",
      "NORD:1497",
      "Orphanet:223",
      "SCTID:111395007",
      "UMLS:C0162283",
      "icd11.foundation:1417669099"
    ],
    "synonyms": [
      "ADH resistant diabetes insipidus",
      "diabetes insipidus nephrogenic",
      "diabetes insipidus nephrogenic X-linked",
      "diabetes insipidus nephrogenic type 1"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "Nephrogenic diabetes insipidus (NDI) is characterized by polyuria with polydipsia, recurrent bouts of fever, constipation, and acute hypernatremic dehydration after birth that may cause neurological sequelae. Polyuria may exceed 10 liters in children."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 3571,
      "label": "impaired renal function disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11705",
          "ICD10CM:N25",
          "ICD9:588.8",
          "ICD9:588.89",
          "ICD9:588.9",
          "MEDGEN:574572",
          "SCTID:197663003",
          "UMLS:C0341677"
        ],
        "synonyms": [
          "disease of kidney",
          "kidney disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "Any disease in which the causes of the disease is a perturbation of the kidney leading to its dysfunction."
      },
      "child_count": 4,
      "reference_id": "MONDO:0001343"
    },
    {
      "id": 6550,
      "label": "diabetes insipidus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9409",
          "ICD10CM:E23.2",
          "ICD9:253.5",
          "MEDGEN:8349",
          "MESH:D003919",
          "NANDO:2100117",
          "NCIT:C43263",
          "SCTID:15771004",
          "UMLS:C0011848"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A disorder characterized by excretion of large amounts of urine, accompanied by excessive thirst. Causes include deficiency of antidiuretic hormone or failure of the kidneys to respond to antidiuretic hormone. It may also be drug-related."
      },
      "child_count": 4,
      "reference_id": "MONDO:0004782"
    },
    {
      "id": 16626,
      "label": "inherited renal tubular disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20667,
        23932
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020306",
          "MEDGEN:1826140",
          "Orphanet:183592",
          "UMLS:C5680544"
        ],
        "synonyms": [
          "genetic renal tubular disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 56,
      "reference_id": "MONDO:0015962"
    }
  ],
  "children": [
    {
      "id": 8841,
      "label": "diabetes insipidus, nephrogenic, autosomal",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16914
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081061",
          "GARD:0015058",
          "MEDGEN:289643",
          "OMIM:125800",
          "UMLS:C1563706"
        ],
        "synonyms": [
          "diabetes insipidus, nephrogenic, 2",
          "diabetes insipidus, nephrogenic, autosomal",
          "diabetes insipidus, nephrogenic, type 2"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0007451"
    },
    {
      "id": 11735,
      "label": "diabetes insipidus, nephrogenic, X-linked",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2902,
        16914
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081060",
          "GARD:0015289",
          "MEDGEN:288785",
          "OMIM:304800",
          "UMLS:C1563705"
        ],
        "synonyms": [
          "diabetes insipidus, nephrogenic, 1, X-linked recessive",
          "diabetes insipidus, nephrogenic, X-linked",
          "Ndi",
          "diabetes insipidus, nephrogenic, type 1"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0010581"
    }
  ],
  "roots": [
    {
      "id": 3571,
      "label": "impaired renal function disease"
    },
    {
      "id": 6550,
      "label": "diabetes insipidus"
    },
    {
      "id": 16626,
      "label": "inherited renal tubular disease"
    }
  ]
}