{
  "id": 16935,
  "label": "hereditary breast carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016419",
  "properties": {
    "xrefs": [
      "GARD:0017142",
      "MEDGEN:87542",
      "MESH:C562840",
      "NCIT:C4503",
      "OMIM:114480",
      "Orphanet:227535",
      "SCTID:254843006",
      "UMLS:C0346153"
    ],
    "synonyms": [
      "breast cancer susceptibility, autosomal dominant, somatic mutation",
      "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation",
      "breast cancer, invasive ductal, autosomal dominant, somatic mutation",
      "breast cancer, lobular, somatic",
      "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation",
      "breast cancer, protection against, autosomal dominant, somatic mutation",
      "breast cancer, somatic",
      "breast cancer, susceptibility to, autosomal dominant, somatic mutation",
      "familial breast cancer",
      "familial breast carcinoma",
      "familial cancer of breast",
      "familial cancer of the breast",
      "hereditary breast cancer",
      "hereditary breast carcinoma",
      "breast cancer, familial",
      "breast cancer, familial Male"
    ],
    "categories": [
      {
        "ref": "MONDO:0002657",
        "name": "breast disorder"
      }
    ],
    "definition": "Breast carcinoma that has developed in relatives of patients with history of breast carcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 5714,
      "label": "hereditary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:630",
          "EFO:0000508",
          "ICD9:799.89",
          "MEDGEN:5527",
          "MESH:D030342",
          "NCIT:C3101",
          "SCTID:32895009",
          "UMLS:C0019247"
        ],
        "synonyms": [
          "genetic condition",
          "genetic disease",
          "genetic disorder",
          "hereditary disease",
          "hereditary disease or disorder",
          "hereditary diseases",
          "inherited disease",
          "inherited genetic disease",
          "molecular disease",
          "Mendelian disease",
          "familial disorder",
          "inborn disorder"
        ],
        "definition": "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome."
      },
      "child_count": 1925,
      "reference_id": "MONDO:0003847"
    },
    {
      "id": 6730,
      "label": "breast carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6734,
        8659
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3459",
          "EFO:0000305",
          "HP:0003002",
          "MEDGEN:146260",
          "NCIT:C4872",
          "SCTID:254838004",
          "UMLS:C0678222"
        ],
        "synonyms": [
          "breast cancer",
          "breast cancer, NOS",
          "cancer of breast",
          "cancer of the breast",
          "cancer, breast",
          "breast carcinoma",
          "carcinoma of breast",
          "carcinoma of the breast",
          "mammary carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          }
        ],
        "definition": "A carcinoma that arises from epithelial cells of the breast"
      },
      "child_count": 26,
      "reference_id": "MONDO:0004989"
    }
  ],
  "children": [
    {
      "id": 23994,
      "label": "CTNNA1-related diffuse gastric and lobular breast cancer syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2991,
        6770,
        16935,
        18536
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026099"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002657",
            "name": "breast disorder"
          },
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Germline pathogenic or likely pathogenic variants in the CTNNA1 gene predispose to hereditary diffuse gastric cancer and lobular breast cancer, a cancer susceptibility syndrome inherited in an autosomal dominant pattern."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100256"
    }
  ],
  "roots": [
    {
      "id": 5714,
      "label": "hereditary disease"
    },
    {
      "id": 6730,
      "label": "breast carcinoma"
    }
  ]
}