{
  "id": 16944,
  "label": "Balo concentric sclerosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016430",
  "properties": {
    "xrefs": [
      "DOID:0060215",
      "GARD:0005885",
      "MEDGEN:498",
      "MedDRA:10010252",
      "NANDO:1200028",
      "NORD:835",
      "Orphanet:228165",
      "SCTID:230380005",
      "UMLS:C0004712"
    ],
    "synonyms": [
      "Balo Disease",
      "Balo concentric sclerosis",
      "Balo's concentric sclerosis",
      "concentric demyelination",
      "Balo disease",
      "Balo's disease",
      "Baló concentric sclerosis",
      "Marburg variant",
      "Tumefactive multiple sclerosis",
      "diffuse cerebral sclerosis of Schilder",
      "encephalitis periaxialis concentrica"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Tumefactive multiple sclerosis is characterized by a tumor-like lesion larger than two centimeters and signs and symptoms similar to those of a brain tumor. It is a rare form of multiple sclerosis (MS). Symptoms of tumefactive MS often differ from other MS cases and may include, headaches, changes in thinking, confusion, speech problems, seizures, and weakness. The cause of tumefactive MS is not known. It often develops into the relapsing-remitting form of MS. In other cases there is only one occurrence of the condition. In still others the disease process remains less clear. While there is no cure for tumefactive MS, treatments such as corticosteroids are available to decrease disease activity."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4626,
      "label": "demyelinating disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7208,
        20383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3213",
          "MEDGEN:4189",
          "MESH:D003711",
          "NCIT:C34527",
          "UMLS:C0011303"
        ],
        "synonyms": [
          "demyelinating disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A broad group of disorders that affect the myelin sheaths that cover the neurons. Myelin sheathes cover neuronal axons in the central and peripheral nervous system and function to increase traveling impulse speeds. Disruption of this sheath impairs neuronal transmission and can result in disorders such as multiple sclerosis and Guillain-Barre syndrome, among others."
      },
      "child_count": 16,
      "reference_id": "MONDO:0002562"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4626,
      "label": "demyelinating disease"
    }
  ]
}