{
  "id": 17011,
  "label": "ectopic aldosterone-producing tumor",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016506",
  "properties": {
    "xrefs": [
      "GARD:0020622",
      "MEDGEN:1654612",
      "Orphanet:231632",
      "UMLS:C4755311"
    ],
    "synonyms": [
      "Extra-adrenal aldosterone-producing tumor",
      "Extra-adrenal aldosterone-producing tumour"
    ],
    "categories": [
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Ectopic aldosterone-producing tumor is an extremely rare aldosterone-producing neoplasm composed of aberrant adrenocortical tissue located outside the adrenal glands (e.g. in retroperitoneum, perirenal or periaortic fatty tissue, thorax, spinal canal, testes, ovaries) typically characterized by symptoms related to increased aldosterone levels (such as sustained, treatment-resistant hypertension and hypokalemia) or symptoms caused by local tumor enlargement."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 3643,
      "label": "primary aldosteronism",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5007
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12028",
          "ICD10CM:E26.0",
          "ICD10CM:E26.01",
          "ICD9:255.12",
          "MEDGEN:278002",
          "NANDO:2200361",
          "NCIT:C34510",
          "SCTID:190507007",
          "UMLS:C1384514",
          "icd11.foundation:197924221"
        ],
        "synonyms": [
          "Conn syndrome",
          "Conn's syndrome",
          "primary aldosteronism",
          "primary hyperaldosteronism"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An endocrine disorder characterized by excessive production of aldosterone by the adrenal glands. Causes include adrenal gland adenoma and adrenal gland hyperplasia. The overproduction of aldosterone results in sodium and water retention and hypokalemia. Patients present with high blood pressure, muscle weakness, and headache."
      },
      "child_count": 4,
      "reference_id": "MONDO:0001422"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 3643,
      "label": "primary aldosteronism"
    }
  ]
}