{
  "id": 17035,
  "label": "congenital secondary polycythemia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016540",
  "properties": {
    "xrefs": [
      "GARD:0020635",
      "MEDGEN:1843354",
      "Orphanet:238536",
      "UMLS:C5679848"
    ],
    "synonyms": [
      "congenital secondary erythrocytosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 10564,
      "label": "congenital hematological disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:760584",
          "NCIT:C104003",
          "UMLS:C3267032"
        ],
        "synonyms": [
          "congenital haematological system disease",
          "congenital hematological disorder",
          "congenital hematological system disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A disorder of the blood that is present at birth."
      },
      "child_count": 21,
      "reference_id": "MONDO:0009332"
    },
    {
      "id": 19740,
      "label": "secondary polycythemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7218
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019467",
          "ICD10CM:D75.1",
          "MEDGEN:231144",
          "MedDRA:10036062",
          "NCIT:C27178",
          "Orphanet:98428",
          "UMLS:C1318533"
        ],
        "synonyms": [
          "secondary erythrocytosis",
          "secondary polycythemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Secondary polycythemia is an elevated absolute red blood cell mass caused by enhanced stimulation of red blood cell production by an otherwise normal erythroid lineage that may be congenital or acquired (congenital secondary polycythemia and acquired secondary polycythemia)."
      },
      "child_count": 2,
      "reference_id": "MONDO:0020115"
    }
  ],
  "children": [
    {
      "id": 11095,
      "label": "Chuvash polycythemia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3363,
        17035
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060474",
          "GARD:0017176",
          "MEDGEN:332974",
          "MESH:C563918",
          "OMIM:263400",
          "Orphanet:238557",
          "UMLS:C1837915"
        ],
        "synonyms": [
          "Chuvash polycythemia",
          "VHL familial polycythemia",
          "Von Hippel-Lindau-dependent polycythemia",
          "erythrocytosis, familial, type 2",
          "familial polycythemia caused by mutation in VHL",
          "Chuvash erythrocytosis",
          "ECYT2",
          "erythrocytosis, autosomal recessive benign",
          "erythrocytosis, familial, 2",
          "polycythemia, Chuvash type",
          "polycythemia, VHL-dependent"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Chuvash erythrocytosis is a rare, genetic, congenital secondary polycythemia disorder characterized by increased hemoglobin, hematocrit and erythropoietin serum levels and normal oxygen affinity, which usually manifests with headache, dizziness, dyspnea and/or plethora. Patients present an increased risk of hemorrhage, thrombosis and early death."
      },
      "child_count": 0,
      "reference_id": "MONDO:0009892"
    },
    {
      "id": 17084,
      "label": "autosomal recessive secondary polycythemia not associated with VHL gene",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17035
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020658",
          "Orphanet:247378"
        ],
        "synonyms": [
          "autosomal recessive secondary erythrocytosis not associated with VHL gene",
          "autosomal recessive secondary erythrocytosis, non-Chuvash type",
          "autosomal recessive secondary polycythemia, non-Chuvash type"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0016598"
    }
  ],
  "roots": [
    {
      "id": 10564,
      "label": "congenital hematological disorder"
    },
    {
      "id": 19740,
      "label": "secondary polycythemia"
    }
  ]
}