{
  "id": 17053,
  "label": "familial congenital mirror movements",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016558",
  "properties": {
    "xrefs": [
      "DOID:0111153",
      "GARD:0012551",
      "MEDGEN:473166",
      "OMIMPS:157600",
      "Orphanet:238722",
      "SCTID:229247004",
      "UMLS:C0454455",
      "icd11.foundation:1966778637"
    ],
    "synonyms": [
      "familial congenital controlateral synkinesia",
      "familial congenital mirror movements",
      "hereditary congenital controlateral synkinesia",
      "hereditary congenital mirror movements",
      "isolated congenital controlateral synkinesia",
      "isolated congenital mirror movements",
      "CMM",
      "bimanual synkinesis",
      "congenital mirror movement disorder",
      "congenital mirror movements"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Congenital mirror movement disorder is a condition in which intentional movements of one side of the body are mirrored by involuntary movements of the other side. For example, when an affected individual makes a fist with the right hand, the left hand makes a similar movement. The mirror movements in this disorder primarily involve the upper limbs, especially the hands and fingers. This pattern of movements is present from infancy or early childhood and usually persists throughout life, without other associated signs and symptoms. Intelligence and lifespan are not affected."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 4427,
      "label": "congenital nervous system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6799
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2490",
          "ICD9:742",
          "MEDGEN:105425",
          "NCIT:C97172",
          "UMLS:C0497552"
        ],
        "synonyms": [
          "congenital abnormality of the nervous system",
          "congenital nervous system disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An abnormality of the nervous system that is present at birth or detected in the neonatal period."
      },
      "child_count": 217,
      "reference_id": "MONDO:0002320"
    },
    {
      "id": 7073,
      "label": "movement disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6799
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:480",
          "EFO:0004280",
          "ICD9:333.90",
          "ICD9:333.99",
          "MEDGEN:10113",
          "MESH:D009069",
          "NCIT:C116757",
          "SCTID:60342002",
          "UMLS:C0026650"
        ],
        "synonyms": [
          "movement disease",
          "movement disorder",
          "movement disorders"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Neurological conditions resulting in abnormal voluntary or involuntary movement, which may impact the speed, fluency, quality and ease of movement."
      },
      "child_count": 54,
      "reference_id": "MONDO:0005395"
    },
    {
      "id": 24270,
      "label": "hereditary neurological disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6799
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "neurogenetic disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A heterogeneous group of genetic conditions with Mendelian (autosomal dominant, recessive, or X-linked) or chromosomal etiology characterized by abnormalities in the brain, spinal cord, nerves, or muscles."
      },
      "child_count": 528,
      "reference_id": "MONDO:0100545"
    }
  ],
  "children": [
    {
      "id": 14808,
      "label": "mirror movements 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17053
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070637",
          "GARD:0015814",
          "MEDGEN:482719",
          "OMIM:614508",
          "UMLS:C3281089"
        ],
        "synonyms": [
          "RAD51 familial congenital mirror movements",
          "familial congenital mirror movements caused by mutation in RAD51",
          "mirror movements 2",
          "mirror movements type 2",
          "MRMV2"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Any familial congenital mirror movements in which the cause of the disease is a mutation in the RAD51 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013790"
    },
    {
      "id": 15477,
      "label": "mirror movements 3",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17053
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070639",
          "GARD:0016055",
          "MEDGEN:863561",
          "OMIM:616059",
          "UMLS:C4015124"
        ],
        "synonyms": [
          "DNAL4 familial congenital mirror movements",
          "familial congenital mirror movements caused by mutation in DNAL4",
          "mirror movements 3",
          "mirror movements type 3",
          "MRMV3"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Any familial congenital mirror movements in which the cause of the disease is a mutation in the DNAL4 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014478"
    },
    {
      "id": 22323,
      "label": "mirror movements 4",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17053
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070638",
          "GARD:0016333",
          "MEDGEN:1648342",
          "OMIM:618264",
          "UMLS:C4748869"
        ],
        "synonyms": [
          "MIRROR MOVEMENTS 4",
          "MRMV4"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0032641"
    },
    {
      "id": 24240,
      "label": "mirror movements 1 and/or agenesis of the corpus callosum",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17053
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026260"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A familial congenital mirror movement disorder where individuals with heterozygous variants in DCC have congenital mirror movements and/or agenesis of the corpus callosum (not with or without- some individuals do not demonstrate mirror movements and only have corpus callosum defects, even within the same family)."
      },
      "child_count": 1,
      "reference_id": "MONDO:0100515"
    }
  ],
  "roots": [
    {
      "id": 4427,
      "label": "congenital nervous system disorder"
    },
    {
      "id": 7073,
      "label": "movement disorder"
    },
    {
      "id": 24270,
      "label": "hereditary neurological disease"
    }
  ]
}