{
  "id": 17097,
  "label": "APC-related attenuated familial adenomatous polyposis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016613",
  "properties": {
    "xrefs": [
      "GARD:0017197",
      "Orphanet:247806"
    ],
    "synonyms": [
      "APC-related AFAP",
      "APC-related attenuated FAP",
      "APC-related attenuated familial adenomatous polyposis",
      "APC-related attenuated familial polyposis coli"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      }
    ]
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 16895,
      "label": "attenuated familial adenomatous polyposis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20300
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0008532",
          "MEDGEN:436213",
          "MESH:C538265",
          "NCIT:C6729",
          "Orphanet:220460",
          "SCTID:715866009",
          "UMLS:C2674616",
          "icd11.foundation:1023083906"
        ],
        "synonyms": [
          "AAPC",
          "AFAP",
          "HFAS",
          "attenuated FAP",
          "attenuated adenomatous polyposis coli",
          "attenuated familial adenomatous polyposis",
          "attenuated familial polyposis coli",
          "hereditary flat adenoma syndrome",
          "mild form of FAP"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "Attenuated familial adenomatous polyposis (AFAP) is a mild form of familial adenomatous polyposis characterized by the presence of fewer than 100 adenomatous colonic polyps, a more proximal colonic location, a delayed age of colorectal cancer (CRC) onset and a more limited expression of the extracolonic features."
      },
      "child_count": 1,
      "reference_id": "MONDO:0016362"
    },
    {
      "id": 20299,
      "label": "familial adenomatous polyposis 1",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20300
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080409",
          "GARD:0025282",
          "MEDGEN:398651",
          "OMIM:175100",
          "UMLS:C2713442"
        ],
        "synonyms": [
          "adenomatous polyposis coli",
          "APC-related adenomatous polyposis",
          "FAP1",
          "adenoma, periampullary, somatic",
          "familial adenomatous polyposis 1",
          "Gardner syndrome",
          "adenomatous polyposis coli, attenuated",
          "adenomatous polyposis of the colon",
          "brain tumor-polyposis syndrome 2",
          "familial adenomatous polyposis, attenuated",
          "familial polyposis of the colon",
          "polyposis, adenomatous intestinal"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "An autosomal dominant disorder caused by pathogenic variants in the APC gene, characterized by the development of colorectal adenomatous polyposis, a very high risk of colorectal cancer and other extracolonic manifestations including both classic and attenuated familial adenomatous polyposis (FAP)."
      },
      "child_count": 1,
      "reference_id": "MONDO:0021056"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 16895,
      "label": "attenuated familial adenomatous polyposis"
    },
    {
      "id": 20299,
      "label": "familial adenomatous polyposis 1"
    }
  ]
}