{
  "id": 17158,
  "label": "oligodendroglioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016695",
  "properties": {
    "xrefs": [
      "DOID:3181",
      "EFO:0000632",
      "GARD:0009953",
      "ICDO:9450/3",
      "MEDGEN:45190",
      "MESH:D009837",
      "MedDRA:10030286",
      "NANDO:2200089",
      "NCIT:C3288",
      "ONCOTREE:ODG",
      "Orphanet:251627",
      "UMLS:C0028945"
    ],
    "synonyms": [
      "oligodendroglial neoplasm",
      "oligodendroglial tumor",
      "oligodendroglial tumour",
      "WHO grade II oligodendroglial neoplasm",
      "WHO grade II oligodendroglial tumor",
      "WHO grade II oligodendroglial tumour",
      "oligodendroglioma",
      "well differentiated oligodendroglial tumor",
      "well differentiated oligodendroglial tumour",
      "well differentiated oligodendroglioma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A well-differentiated (WHO grade II), diffusely infiltrating neuroglial tumor, typically located in the cerebral hemispheres. It is composed predominantly of cells which morphologically resemble oligodendroglia. The neoplastic cells have rounded homogeneous nuclei and, on paraffin sections, a swollen, clear cytoplasm ('honeycomb' appearance). (Adapted from WHO)"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 18713,
      "label": "oligodendroglial tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24071
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0013156",
          "MEDGEN:233266",
          "NCIT:C6960",
          "Orphanet:46484",
          "UMLS:C1335110"
        ],
        "synonyms": [
          "oligodendroglial neoplasm",
          "oligodendroglial tumor"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Oligodendrogliomas are cerebral tumors that are differentiated from other gliomas on the basis of their unique genetic characteristics and better response to chemotherapy. These tumors are classified according to their grade (low grade oligodendrogliomas: grade II of the WHO classification and anaplastic oligodendrogliomas: grade III of the WHO classification) and according to their pure or mixed histology (oligoastrocytomas)."
      },
      "child_count": 2,
      "reference_id": "MONDO:0018744"
    },
    {
      "id": 20695,
      "label": "grade II glioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20693
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025345",
          "MEDGEN:1391502",
          "NCIT:C132505",
          "UMLS:C4330050"
        ],
        "synonyms": [
          "WHO grade II glioma",
          "grade II glioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A glioma arising from the central nervous system. This category includes diffuse astrocytoma, ependymoma, oligodendroglioma, and oligoastrocytoma."
      },
      "child_count": 5,
      "reference_id": "MONDO:0021639"
    }
  ],
  "children": [
    {
      "id": 4606,
      "label": "childhood oligodendroglioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8005,
        17158
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3183",
          "GARD:0023156",
          "MEDGEN:76116",
          "NANDO:2200089",
          "NCIT:C4045",
          "UMLS:C0280475"
        ],
        "synonyms": [
          "oligodendroglioma",
          "oligodendroglioma of childhood",
          "paediatric oligodendroglioma",
          "pediatric oligodendroglioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An oligodendroglioma that arises from the central nervous system and occurs during childhood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002540"
    },
    {
      "id": 4607,
      "label": "spinal cord oligodendroglioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4608,
        17158
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3184",
          "GARD:0023157",
          "MEDGEN:138055",
          "NCIT:C4535",
          "SCTID:254950006",
          "UMLS:C0346295"
        ],
        "synonyms": [
          "oligodendroglioma of spinal cord",
          "spinal cord oligodendroglioma",
          "well differentiated spinal cord oligodendroglial tumor",
          "well differentiated spinal cord oligodendroglial tumour",
          "well differentiated spinal cord oligodendroglioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A oligodendroglioma that involves the spinal cord."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002541"
    },
    {
      "id": 4609,
      "label": "adult oligodendroglioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17158
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3186",
          "GARD:0023159",
          "MEDGEN:75924",
          "NANDO:2200089",
          "NCIT:C4014",
          "UMLS:C0279070"
        ],
        "synonyms": [
          "oligodendroglioma",
          "adult oligodendroglioma",
          "grade II adult oligodendroglial tumor",
          "grade II adult oligodendroglial tumour",
          "oligodendroglioma of adults",
          "adult brain oligodendroglioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An oligodendroglioma occurring during adulthood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002543"
    },
    {
      "id": 4610,
      "label": "brain oligodendroglioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7155,
        17158
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3187",
          "GARD:0023160",
          "MEDGEN:91095",
          "NCIT:C9377",
          "SCTID:254940005",
          "UMLS:C0346286"
        ],
        "synonyms": [
          "brain oligodendroglioma",
          "oligodendroglioma of brain",
          "oligodendroglioma of the brain"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A oligodendroglioma that involves the brain."
      },
      "child_count": 2,
      "reference_id": "MONDO:0002544"
    }
  ],
  "roots": [
    {
      "id": 18713,
      "label": "oligodendroglial tumor"
    },
    {
      "id": 20695,
      "label": "grade II glioma"
    }
  ]
}