{
  "id": 17160,
  "label": "low grade ependymoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016697",
  "properties": {
    "xrefs": [
      "Orphanet:251633",
      "icd11.foundation:641455939"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 17161,
      "label": "ependymoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5210,
        20695
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4844",
          "EFO:1000028",
          "GARD:0006353",
          "ICDO:9391/3",
          "MEDGEN:41825",
          "MESH:D004806",
          "MedDRA:10014967",
          "NANDO:2200088",
          "NCIT:C3017",
          "ONCOTREE:EPM",
          "Orphanet:251636",
          "UMLS:C0014474"
        ],
        "synonyms": [
          "benign ependymoma",
          "ependymoma",
          "WHO grade II ependymal neoplasm",
          "WHO grade II ependymal tumor",
          "WHO grade II ependymal tumour",
          "ependymoma, benign",
          "clear cell ependymoma (histologic variant)",
          "ependymoma, familial",
          "papillary ependymoma (histologic variant)",
          "tanycytic ependymoma (histologic variant)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A WHO grade II, slow growing tumor of children and young adults, usually located intraventricularly. It is the most common ependymal neoplasm. It often causes clinical symptoms by blocking cerebrospinal fluid pathways. Key histological features include perivascular pseudorosettes and ependymal rosettes. (WHO)"
      },
      "child_count": 16,
      "reference_id": "MONDO:0016698"
    }
  ],
  "children": [
    {
      "id": 9025,
      "label": "subependymoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17160
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4843",
          "EFO:1000553",
          "GARD:0010070",
          "ICDO:9383/1",
          "MEDGEN:64637",
          "MESH:D018315",
          "NCIT:C3795",
          "ONCOTREE:SUBE",
          "Orphanet:251639",
          "UMLS:C0206725"
        ],
        "synonyms": [
          "SUBEPENDYMOMA, benign",
          "WHO grade I ependymal neoplasm",
          "WHO grade I ependymal tumor",
          "WHO grade I ependymal tumour",
          "subependymal astrocytoma",
          "subependymal glioma",
          "subependymoma",
          "subependymal astrocytoma (formerly)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Subependymoma is a rare and slow growing type of ependymoma, often presenting in middle-aged adults, found more commonly in men than in women, usually located in the fourth and lateral ventricles and manifesting with variable symptoms including headache, nausea, and loss of balance. In some cases it can be asymptomatic. It is usually associated with a better prognosis than other forms of ependymoma."
      },
      "child_count": 1,
      "reference_id": "MONDO:0007667"
    }
  ],
  "roots": [
    {
      "id": 17161,
      "label": "ependymoma"
    }
  ]
}