{
  "id": 17165,
  "label": "anaplastic oligoastrocytoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016703",
  "properties": {
    "xrefs": [
      "EFO:0002500",
      "GARD:0010637",
      "MEDGEN:96556",
      "NCIT:C6959",
      "ONCOTREE:AOAST",
      "Orphanet:251663",
      "UMLS:C0431108"
    ],
    "synonyms": [
      "WHO grade III mixed glioma",
      "aMOA",
      "anaplastic mixed glioma",
      "anaplastic oligoastrocytoma",
      "AOAST"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "An oligoastrocytoma characterized by the presence of increased cellularity, nuclear atypia, pleomorphism, and high mitotic activity."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7464,
      "label": "malignant mixed neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        20288
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:154",
          "EFO:1000356",
          "ICDO:8940/3",
          "MEDGEN:64618",
          "MESH:D018198",
          "NCIT:C3729",
          "UMLS:C0206625"
        ],
        "synonyms": [
          "mixed cell type cancer",
          "mixed neoplasm",
          "mixed tumor",
          "mixed tumour",
          "malignant mixed neoplasm",
          "malignant mixed tumor",
          "malignant mixed tumour",
          "mixed neoplasm, malignant",
          "mixed tumor, malignant (morphologic abnormality)",
          "mixed tumor, malignant, NOS (morphologic abnormality)",
          "tumor, mixed, malignant",
          "malignant mixed tumors",
          "malignant mixed tumours",
          "mixed tumors, malignant",
          "tumor, malignant mixed",
          "tumors, malignant mixed"
        ],
        "definition": "A malignant neoplasm composed of a carcinomatous epithelial component and a sarcomatous mesenchymal component. Representative examples include malignant mixed mesodermal (Mullerian) tumor of the female reproductive system and carcinosarcoma of the salivary gland and the lung."
      },
      "child_count": 30,
      "reference_id": "MONDO:0005853"
    },
    {
      "id": 17164,
      "label": "oligoastrocytoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5211,
        20695
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7912",
          "EFO:0000630",
          "GARD:0009769",
          "MEDGEN:154285",
          "MedDRA:10027744",
          "NCIT:C4050",
          "ONCOTREE:OAST",
          "Orphanet:251656",
          "SCTID:716647001",
          "UMLS:C0547065"
        ],
        "synonyms": [
          "MOA",
          "WHO grade II mixed glioma",
          "glioma, mixed, benign",
          "mixed astrocytic-oligodendroglial neoplasm",
          "mixed astrocytic-oligodendroglial tumor",
          "mixed astrocytic-oligodendroglial tumour",
          "mixed astrocytoma-oligodendroglioma",
          "mixed oligo-astrocytoma",
          "mixed oligoastrocytoma",
          "mixed oligodendroglioma-astrocytoma",
          "oligoastrocytoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A WHO grade II tumor composed of a conspicuous mixture of two distinct neoplastic cell types morphologically resembling the tumor cells in oligodendroglioma and diffuse astrocytoma. (WHO)"
      },
      "child_count": 2,
      "reference_id": "MONDO:0016702"
    },
    {
      "id": 20048,
      "label": "anaplastic cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:231373",
          "NCIT:C36025",
          "UMLS:C1332287"
        ],
        "synonyms": [
          "anaplastic malignant neoplasm"
        ]
      },
      "child_count": 8,
      "reference_id": "MONDO:0020633"
    },
    {
      "id": 20696,
      "label": "grade III glioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24071
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025346",
          "MEDGEN:925529",
          "NCIT:C127816",
          "UMLS:C4287997"
        ],
        "synonyms": [
          "WHO grade III glioma",
          "anaplastic glioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A group of malignant gliomas that includes anaplastic astrocytoma, anaplastic oligodendroglioma, anaplastic oligoastrocytoma, and anaplastic ependymoma."
      },
      "child_count": 3,
      "reference_id": "MONDO:0021640"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7464,
      "label": "malignant mixed neoplasm"
    },
    {
      "id": 17164,
      "label": "oligoastrocytoma"
    },
    {
      "id": 20048,
      "label": "anaplastic cancer"
    },
    {
      "id": 20696,
      "label": "grade III glioma"
    }
  ]
}