{
  "id": 17174,
  "label": "ependymoblastoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016715",
  "properties": {
    "xrefs": [
      "DOID:0080903",
      "DOID:4794",
      "GARD:0020720",
      "MEDGEN:152150",
      "MedDRA:10014966",
      "NCIT:C4915",
      "ONCOTREE:ETANTR",
      "Orphanet:251880",
      "SCTID:715901002",
      "UMLS:C0700367"
    ],
    "synonyms": [
      "ETMR, C19MC-altered",
      "embryonal tumor with Multilayered Rosettes",
      "embryonal tumor with Multilayered Rosettes with C19MC amplification",
      "embryonal tumor with Multilayered Rosettes, C19MC-altered",
      "embryonal tumor with abundant neuropil and true Rosettes",
      "embryonal tumour with Multilayered Rosettes",
      "embryonal tumour with Multilayered Rosettes with C19MC amplification",
      "embryonal tumour with Multilayered Rosettes, C19MC-altered",
      "embryonal tumour with abundant neuropil and true Rosettes",
      "ependymoblastoma",
      "ETANTR",
      "ETMR",
      "embryonal tumor with abundant neuropil and true rosettes",
      "embryonal tumour with abundant neuropil and true rosettes",
      "neuroectodermal tumors primitive",
      "neuroectodermal tumours primitive"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Ependymoblastoma is a rare type of primitive neuroectodermal tumor (PNET) that usually occurs in young children under the age of 2 and is histologically distinguished by the production of ependymoblastic rosettes. It is associated with an aggressive course and a poor prognosis."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 3043,
      "label": "central nervous system primitive neuroectodermal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4753,
        7121
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060103",
          "GARD:0027536",
          "MEDGEN:854517",
          "NANDO:2200099",
          "NANDO:2200100",
          "NCIT:C5398",
          "UMLS:C3887678",
          "icd11.foundation:1711526170"
        ],
        "synonyms": [
          "CNS PNET",
          "CNS primitive neuroectodermal neoplasm",
          "CNS primitive neuroectodermal tumor",
          "CNS primitive neuroectodermal tumour",
          "central nervous system PNET",
          "central nervous system neuroectodermal tumor",
          "central nervous system neuroectodermal tumour",
          "central nervous system primitive neuroectodermal neoplasm",
          "central nervous system primitive neuroectodermal tumor",
          "central nervous system primitive neuroectodermal tumor (WHO grade IV)",
          "central nervous system primitive neuroectodermal tumour",
          "central nervous system primitive neuroectodermal tumour (WHO grade IV)",
          "central primitive neuroectodermal neoplasm",
          "central primitive neuroectodermal tumor",
          "central primitive neuroectodermal tumour",
          "primitive neuroectodermal tumor of central nervous system",
          "primitive neuroectodermal tumour of central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A neuroectodermal tumor that involves the central nervous system."
      },
      "child_count": 16,
      "reference_id": "MONDO:0000640"
    },
    {
      "id": 17173,
      "label": "central nervous system Ewing sarcoma/peripheral primitive neuroectodermal tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4753,
        20283
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020718",
          "MEDGEN:1389430",
          "MedDRA:10057846",
          "NCIT:C129537",
          "Orphanet:251870",
          "UMLS:C4329632"
        ],
        "synonyms": [
          "central nervous system PNET",
          "central nervous system Ewing sarcoma/peripheral primitive neuroectodermal tumor",
          "CNS PNET",
          "central nervous system primitive neuroectodermal tumor",
          "central nervous system primitive neuroectodermal tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare Ewing sarcoma/peripheral primitive neuroectodermal tumor that affects the central nervous system either as a primary dural neoplasm or by direct extension from adjacent soft tissues or bone."
      },
      "child_count": 8,
      "reference_id": "MONDO:0016713"
    }
  ],
  "children": [
    {
      "id": 6083,
      "label": "pediatric infratentorial ependymoblastoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4825,
        4922,
        5088,
        5116,
        17174
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7522",
          "GARD:0023903",
          "MEDGEN:272462",
          "NCIT:C6773",
          "UMLS:C1332972"
        ],
        "synonyms": [
          "childhood infratentorial embryonal tumor with Multilayered Rosettes, C19MC-altered",
          "childhood infratentorial embryonal tumour with Multilayered Rosettes, C19MC-altered",
          "childhood infratentorial ependymoblastoma",
          "pediatric infratentorial ependymoblastoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An embryonal tumor with multilayered rosettes, C19MC-altered that arises from the infratentorial region and occurs in children."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004263"
    },
    {
      "id": 6126,
      "label": "adult embryonal tumor with multilayered rosettes, c19mc-altered",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4822,
        17174
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7631",
          "GARD:0023925",
          "MEDGEN:83792",
          "NCIT:C8290",
          "UMLS:C0281330"
        ],
        "synonyms": [
          "embryonal tumor with multilayered rosettes, C19MC-altered",
          "embryonal tumour with multilayered rosettes, C19MC-altered",
          "adult embryonal tumor with multilayered rosettes, C19MC-altered",
          "adult embryonal tumour with multilayered rosettes, C19MC-altered",
          "adult ependymoblastoma",
          "ependymoblastoma of adults"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An embryonal tumor with multilayered rosettes, C19MC-altered, occurring in adults."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004310"
    },
    {
      "id": 6191,
      "label": "pediatric cerebral ependymoblastoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4768,
        4825,
        5116,
        17174
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7841",
          "GARD:0023969",
          "MEDGEN:234125",
          "NCIT:C6957",
          "UMLS:C1332962"
        ],
        "synonyms": [
          "childhood cerebral embryonal tumor with Multilayered Rosettes, C19MC-altered",
          "childhood cerebral embryonal tumour with Multilayered Rosettes, C19MC-altered",
          "childhood cerebral ependymoblastoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An embryonal tumor with multilayered rosettes, C19MC-altered that arises from the cerebral hemispheres and occurs in children."
      },
      "child_count": 4,
      "reference_id": "MONDO:0004378"
    }
  ],
  "roots": [
    {
      "id": 3043,
      "label": "central nervous system primitive neuroectodermal neoplasm"
    },
    {
      "id": 17173,
      "label": "central nervous system Ewing sarcoma/peripheral primitive neuroectodermal tumor"
    }
  ]
}