{
  "id": 17176,
  "label": "choroid plexus carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016718",
  "properties": {
    "xrefs": [
      "DOID:5648",
      "GARD:0008238",
      "ICDO:9390/3",
      "MEDGEN:96557",
      "MESH:C562943",
      "MedDRA:10067478",
      "NCIT:C4715",
      "ONCOTREE:CPC",
      "Orphanet:251899",
      "SCTID:188292007",
      "UMLS:C0431109",
      "icd11.foundation:1128449352"
    ],
    "synonyms": [
      "cancer of choroid plexus",
      "cancer of the choroid plexus",
      "choroid plexus cancer",
      "malignant neoplasm of choroid plexus",
      "malignant neoplasm of the choroid plexus",
      "malignant tumor of choroid plexus",
      "malignant tumour of choroid plexus",
      "anaplastic choroid plexus papilloma",
      "carcinoma of choroid plexus",
      "carcinoma of the choroid plexus",
      "carcinoma, choroid plexus, malignant",
      "choroid plexus carcinoma",
      "choroid plexus carcinoma (morphologic abnormality)"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A malignant neoplasm arising from the choroid plexus. It shows anaplastic features and usually invades neighboring brain structures. Cerebrospinal fluid metastases are frequent. (Adapted from WHO)"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4728,
      "label": "choroid plexus cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4233,
        4729,
        17175,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3540",
          "EFO:0007206",
          "GARD:0023212",
          "MEDGEN:138053",
          "NCIT:C4533",
          "UMLS:C0346289"
        ],
        "synonyms": [
          "choroid plexus neoplasm",
          "tumor of choroid plexus",
          "tumour of choroid plexus",
          "tumour of the choroid plexus",
          "cancer of choroid plexus",
          "choroid plexus cancer",
          "malignant choroid plexus neoplasm",
          "malignant choroid plexus neoplasms",
          "malignant choroid plexus tumor",
          "malignant choroid plexus tumors",
          "malignant choroid plexus tumour",
          "malignant choroid plexus tumours",
          "malignant neoplasm of choroid plexus",
          "malignant neoplasm of the choroid plexus",
          "malignant tumor of choroid plexus",
          "malignant tumor of the choroid plexus",
          "malignant tumour of choroid plexus",
          "malignant tumour of the choroid plexus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the choroid plexus"
      },
      "child_count": 8,
      "reference_id": "MONDO:0002681"
    },
    {
      "id": 6734,
      "label": "carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        7265
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2000-1867",
          "DOID:305",
          "EFO:0000313",
          "ICDO:8010/3",
          "ICDO:8011/3",
          "MEDGEN:2867",
          "MESH:D002277",
          "NCIT:C2916",
          "SCTID:722688002",
          "UMLS:C0007097"
        ],
        "synonyms": [
          "epithelioma",
          "Other carcinoma",
          "carcinoma",
          "carcinoma, malignant",
          "epithelial carcinoma",
          "epithelioma malignant",
          "malignant epithelial neoplasm",
          "malignant epithelial tumor",
          "malignant epithelial tumour",
          "malignant epithelioma"
        ],
        "definition": "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas."
      },
      "child_count": 98,
      "reference_id": "MONDO:0004993"
    }
  ],
  "children": [
    {
      "id": 4732,
      "label": "childhood choroid plexus carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4214,
        8005,
        17176,
        21583
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3545",
          "GARD:0023214",
          "MEDGEN:901899",
          "NCIT:C124292",
          "UMLS:C1510426"
        ],
        "synonyms": [
          "childhood choroid plexus neoplasm",
          "childhood choroid plexus carcinoma",
          "choroid plexus carcinoma of childhood",
          "paediatric choroid plexus carcinoma",
          "pediatric choroid plexus carcinoma",
          "childhood choroid plexus cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A choroid plexus carcinoma that occurs during childhood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002685"
    }
  ],
  "roots": [
    {
      "id": 4728,
      "label": "choroid plexus cancer"
    },
    {
      "id": 6734,
      "label": "carcinoma"
    }
  ]
}