{
  "id": 17178,
  "label": "pineoblastoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016722",
  "properties": {
    "xrefs": [
      "DOID:1664",
      "EFO:1000475",
      "GARD:0009369",
      "ICDO:9362/3",
      "MEDGEN:104745",
      "MedDRA:10050487",
      "NCIT:C9344",
      "ONCOTREE:PBL",
      "Orphanet:251909",
      "UMLS:C0205898"
    ],
    "synonyms": [
      "PNET of pineal gland",
      "PNET of the pineal gland",
      "pineal PNET",
      "pineal gland PNET",
      "pineal gland primitive neuroectodermal neoplasm",
      "pineal gland primitive neuroectodermal tumor",
      "pineal gland primitive neuroectodermal tumour",
      "pineal primitive neuroectodermal neoplasm",
      "pineal primitive neuroectodermal tumor",
      "pineal primitive neuroectodermal tumour",
      "pineoblastoma",
      "pineoblastoma (WHO grade IV)",
      "pineoblastoma, malignant",
      "primitive neuroectodermal neoplasm of pineal gland",
      "primitive neuroectodermal neoplasm of the pineal gland",
      "primitive neuroectodermal tumor of pineal gland",
      "primitive neuroectodermal tumor of the pineal gland",
      "primitive neuroectodermal tumour of pineal gland",
      "primitive neuroectodermal tumour of the pineal gland"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Pineoblastoma is a rare, malignant type of supratentorial primitive neuroectodermal tumor (sPNET), found mainly in children (less than 10% of cases are reported in adults), and located in the pineal region of the brain but that can metastasize along the neuroaxis. As it is the most aggressive of the pineal parenchymal tumors, it is usually associated with a poor prognosis."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 5194,
      "label": "pineal gland cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5646,
        20310,
        20442
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5032",
          "GARD:0027637",
          "ICD10CM:C75.3",
          "ICD9:194.4",
          "MEDGEN:102284",
          "NCIT:C3573",
          "SCTID:363483004",
          "UMLS:C0153655"
        ],
        "synonyms": [
          "neoplasm of the pineal region",
          "pineocytic tumor",
          "pineocytic tumour",
          "tumor of the pineal region",
          "tumour of the pineal region",
          "cancer of pineal body",
          "malignant neoplasm of pineal body",
          "malignant neoplasm of pineal gland",
          "malignant neoplasm of the pineal gland",
          "malignant pineal area neoplasm",
          "malignant pineal area tumor",
          "malignant pineal area tumour",
          "malignant pineal body neoplasm",
          "malignant pineal gland neoplasm",
          "malignant pineal gland tumor",
          "malignant pineal gland tumour",
          "malignant pineal region neoplasm",
          "malignant pineal region tumor",
          "malignant pineal region tumour",
          "malignant tumor of pineal gland",
          "malignant tumor of the pineal gland",
          "malignant tumour of pineal gland",
          "malignant tumour of the pineal gland",
          "pineal body cancer",
          "pinealoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Abnormal malignant growth of the cells that comprise the pineal parenchyma."
      },
      "child_count": 9,
      "reference_id": "MONDO:0003249"
    },
    {
      "id": 7212,
      "label": "embryonal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:688",
          "EFO:0005784",
          "MEDGEN:45034",
          "NCIT:C3264",
          "ONCOTREE:EMBT",
          "UMLS:C0027654"
        ],
        "synonyms": [
          "embryonal neoplasm",
          "embryonal tumor",
          "embryonal tumour",
          "EMBT",
          "embryonal cancer"
        ],
        "definition": "A usually malignant neoplasm composed of primitive (immature) tissues that resemble fetal tissues. Medulloblastoma, Ependymoblastoma, Pineoblastoma, and Wilms tumor are representative embryonal neoplasms. --2003"
      },
      "child_count": 12,
      "reference_id": "MONDO:0005564"
    }
  ],
  "children": [
    {
      "id": 5815,
      "label": "adult pineoblastoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5193,
        17178
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6648",
          "GARD:0023751",
          "MEDGEN:83794",
          "NCIT:C8292",
          "UMLS:C0281332"
        ],
        "synonyms": [
          "pineoblastoma",
          "adult pineoblastoma",
          "pineoblastoma of adults"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A pineoblastoma occurring in adults."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003957"
    }
  ],
  "roots": [
    {
      "id": 5194,
      "label": "pineal gland cancer"
    },
    {
      "id": 7212,
      "label": "embryonal neoplasm"
    }
  ]
}