{
  "id": 17185,
  "label": "ganglioglioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016733",
  "properties": {
    "xrefs": [
      "DOID:5078",
      "EFO:0003094",
      "GARD:0002430",
      "ICDO:9505/1",
      "MEDGEN:60216",
      "MESH:D018303",
      "MedDRA:10017701",
      "NANDO:2200096",
      "NCIT:C3788",
      "ONCOTREE:GNG",
      "Orphanet:251949",
      "SCTID:87191000119100",
      "UMLS:C0206716",
      "icd11.foundation:1287417975"
    ],
    "synonyms": [
      "ganglioglioma",
      "adult ganglioglioma",
      "childhood ganglioglioma",
      "mixed cell tumors containing both neural ganglionic cells and neural glial cell components",
      "mixed cell tumours containing both neural ganglionic cells and neural glial cell components"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A well differentiated, slow growing neuroepithelial neoplasm composed of neoplastic, mature ganglion cells and neoplastic glial cells. Some gangliogliomas show anaplastic features in their glial component and are considered to be WHO grade III. Rare cases of newly diagnosed gangliogliomas with grade IV (glioblastoma) changes in the glial component have also been reported. (Adapted from WHO)"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 17182,
      "label": "mixed neuronal-glial tumor",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        20418
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020728",
          "MEDGEN:105377",
          "NCIT:C4747",
          "Orphanet:251934",
          "UMLS:C0474844",
          "icd11.foundation:1792897751"
        ],
        "synonyms": [
          "neuronal and Glio-neuronal neoplasm",
          "neuronal and Glio-neuronal tumor",
          "neuronal and Glio-neuronal tumour",
          "neuronal and mixed neuronal-glial tumor",
          "neuronal and mixed neuronal-glial tumors",
          "neuronal and mixed neuronal-glial tumour",
          "neuronal and mixed neuronal-glial tumours"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A group of central nervous system neoplasms with a variable amount of neuronal and, less consistently, glial differentiation. They occur at a low frequency and usually carry a favorable prognosis. Representative examples include dysplastic cerebellar gangliocytoma, desmoplastic infantile ganglioglioma, desmoplastic infantile astrocytoma, and dysembryoplastic neuroepithelial tumor. (Adapted from WHO)"
      },
      "child_count": 12,
      "reference_id": "MONDO:0016729"
    }
  ],
  "children": [
    {
      "id": 16246,
      "label": "nasal ganglioglioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7231,
        17185,
        21538
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019950",
          "MEDGEN:1786513",
          "Orphanet:141115",
          "UMLS:C5548206",
          "icd11.foundation:40917416"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "Nasal ganglioglioma is a rare tumor, presenting in newborns, containing both neuronal and astrocytic components and that can be endonasal, extranasal or both. It is usually identified as a nasal mass that may cause feeding difficulties and nasal obstruction."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015393"
    },
    {
      "id": 17186,
      "label": "anaplastic ganglioglioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17185
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0010639",
          "ICDO:9505/3",
          "MEDGEN:140906",
          "NCIT:C4717",
          "ONCOTREE:AGNG",
          "Orphanet:251957",
          "UMLS:C0431112"
        ],
        "synonyms": [
          "AGNG"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A WHO grade III neuroepithelial neoplasm composed of neoplastic, mature ganglion cells and anaplastic glial cells. The anaplastic changes in the glial component and high MIB-1 and TP53 labeling indices may indicate aggressive behavior. However, the correlation of histological anaplasia with clinical outcome is inconsistent. (Adapted from WHO)"
      },
      "child_count": 0,
      "reference_id": "MONDO:0016734"
    }
  ],
  "roots": [
    {
      "id": 17182,
      "label": "mixed neuronal-glial tumor"
    }
  ]
}