{
  "id": 17226,
  "label": "complete hydatidiform mole",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016785",
  "properties": {
    "xrefs": [
      "GARD:0017224",
      "MEDGEN:195706",
      "NCIT:C4871",
      "ONCOTREE:CHM",
      "Orphanet:254688",
      "SCTID:237249000",
      "UMLS:C0678213",
      "icd11.foundation:1338299833"
    ],
    "synonyms": [
      "classical hydatidiform Mole",
      "complete Mole",
      "complete hydatid Mole",
      "complete molar pregnancy"
    ],
    "categories": [
      {
        "ref": "MONDO:0005039",
        "name": "reproductive system disorder"
      }
    ],
    "definition": "Complete hydatidiform mole is a type of hydatiform mole characterized by abnormal hyperplastic trophoblasts and hydropic villi due to fertilization of an enucleated ovocyte by one or two haploid spermatozoa that can manifest with vaginal bleeding accompanied by nausea and frequent vomiting, hyperemesis gravidarum, risk of spontaneous miscarriage, hyperthyroidism, and has the potential of developing into choriocarcinoma."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 7798,
      "label": "hydatidiform mole",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4886,
        5714,
        20430
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000298",
          "GARD:0010263",
          "ICD10WHO:O01",
          "ICD9:631",
          "ICDO:9100/0",
          "MEDGEN:9329",
          "MESH:D006828",
          "MedDRA:10020481",
          "NCIT:C3110",
          "OMIMPS:231090",
          "ONCOTREE:MP",
          "Orphanet:99927",
          "SCTID:44782008",
          "UMLS:C0020217",
          "icd11.foundation:946166369"
        ],
        "synonyms": [
          "hydatid mole",
          "hydatidiform mole",
          "molar pregnancy",
          "HYDM",
          "hydatidiform mole, recurrent"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A gestational trophoblastic disorder characterized by marked enlargement of the chorionic villi, hyperplasia of the villous trophoblastic cells and hydropic changes."
      },
      "child_count": 15,
      "reference_id": "MONDO:0006248"
    }
  ],
  "children": [
    {
      "id": 10514,
      "label": "hydatidiform mole, recurrent, 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17226,
        18866
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018365",
          "MEDGEN:483038",
          "OMIM:231090",
          "UMLS:C3463897"
        ],
        "synonyms": [
          "NLRP7 complete hydatidiform mole",
          "complete hydatidiform mole caused by mutation in NLRP7",
          "hydatidiform Mole, recurrent, type 1",
          "hydatidiform mole, recurrent, 1",
          "HYDM1",
          "gestational trophoblastic disease",
          "hydatidiform MOLE, recurrent, 1",
          "hydatidiform Mole, complete",
          "hydatidiform mole"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Any complete hydatidiform mole in which the cause of the disease is a mutation in the NLRP7 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0009273"
    },
    {
      "id": 14694,
      "label": "hydatidiform mole, recurrent, 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17226,
        18866
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018366",
          "MEDGEN:481982",
          "OMIM:614293",
          "UMLS:C3280352"
        ],
        "synonyms": [
          "KHDC3L complete hydatidiform mole",
          "complete hydatidiform mole caused by mutation in KHDC3L",
          "hydatidiform Mole, recurrent, type 2",
          "hydatidiform mole, recurrent, 2",
          "HYDM2",
          "hydatidiform MOLE, recurrent, 2",
          "hydatidiform Mole, complete"
        ],
        "categories": [
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "Any complete hydatidiform mole in which the cause of the disease is a mutation in the KHDC3L gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013671"
    }
  ],
  "roots": [
    {
      "id": 7798,
      "label": "hydatidiform mole"
    }
  ]
}