{
  "id": 17387,
  "label": "thymoma type AB",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0016975",
  "properties": {
    "xrefs": [
      "DOID:3280",
      "EFO:1000582",
      "GARD:0020894",
      "ICDO:8582/1",
      "MEDGEN:220414",
      "NCIT:C6885",
      "Orphanet:263324",
      "UMLS:C1266092"
    ],
    "synonyms": [
      "mixed type thymoma",
      "primary thymic epithelial neoplasm type AB",
      "primary thymic epithelial tumor type AB",
      "primary thymic epithelial tumour type AB",
      "thymoma type AB"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A thymic epithelial neoplasm characterized by the presence of a lymphocyte-poor component similar to that seen in type A thymoma and a lymphocyte-rich component which contains neoplastic small polygonal epithelial cells. It may be associated with myasthenia gravis and pure red cell aplasia. The majority of cases occur in the anterior mediastinum as Masaoka stage I tumors. A minority of the cases occur as stage II or stage III tumors. The overall survival is reported to be 80-100% at 5 and 10 years."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 7959,
      "label": "thymoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18240
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3275",
          "EFO:1000581",
          "GARD:0016922",
          "HP:0100522",
          "ICD9:239.89",
          "ICDO:8580/1",
          "MEDGEN:52743",
          "MESH:D013945",
          "MedDRA:10043670",
          "NCIT:C3411",
          "ONCOTREE:THYM",
          "Orphanet:99867",
          "SCTID:444231005",
          "UMLS:C0040100",
          "icd11.foundation:33869057"
        ],
        "synonyms": [
          "primary thymic epithelial neoplasm",
          "primary thymic epithelial tumor",
          "primary thymic epithelial tumour",
          "thymoma",
          "thymoma (disease)",
          "THYM"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A neoplasm arising from the epithelial cells of the thymus. Although thymomas are usually encapsulated tumors, they may invade the capsule and infiltrate the surrounding tissues or even metastasize to distant anatomic sites. The following morphologic subtypes are currently recognized: type A, type B, type AB, metaplastic, micronodular, microscopic, and sclerosing thymoma. Thymomas type B are further subdivided into types B1, B2, and B3. Thymoma type B3 usually has the most aggressive clinical course."
      },
      "child_count": 8,
      "reference_id": "MONDO:0006456"
    }
  ],
  "children": [
    {
      "id": 5832,
      "label": "malignant type AB thymoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7956,
        17387
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6723",
          "GARD:0023758",
          "ICDO:8582/3",
          "MEDGEN:224760",
          "NCIT:C6886",
          "UMLS:C1266093"
        ],
        "synonyms": [
          "malignant thymoma type AB",
          "malignant type AB thymoma",
          "thymoma type AB, malignant"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A type AB thymoma which is characterized by an aggressive clinical course (capsular invasion, infiltration of the surrounding tissues) and can metastasize."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003976"
    }
  ],
  "roots": [
    {
      "id": 7959,
      "label": "thymoma"
    }
  ]
}