{
  "id": 17426,
  "label": "congenital mesoblastic nephroma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017043",
  "properties": {
    "xrefs": [
      "DOID:4773",
      "GARD:0001493",
      "ICDO:8960/1",
      "MEDGEN:232058",
      "MedDRA:10070665",
      "NCIT:C6569",
      "Orphanet:2665",
      "UMLS:C1332965",
      "icd11.foundation:2001572901"
    ],
    "synonyms": [
      "mesoblastic nephroma",
      "CMN",
      "CMn",
      "congenital mesoblastic nephroma",
      "stromal nephroma, malignant"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A low grade childhood congenital malignant neoplasm arising from the kidney. It is characterized by the presence of fibroblastic cells. The majority of cases occur in the first year of life. Complete excision is usually associated with an excellent prognosis."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 5106,
      "label": "mesoblastic nephroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4465
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4772",
          "EFO:0007365",
          "ICD9:236.99",
          "MEDGEN:64620",
          "MESH:D018201",
          "SCTID:307604008",
          "UMLS:C0206628"
        ],
        "synonyms": [
          "mesoblastic nephroma",
          "mesoblastic nephroma (morphologic abnormality)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A solid, unencapsulated tumor of the kidney composed of spindle mesenchymal cells that resemble fibroblasts or muscle cells. The homogeneous mass typically extends into the renal parenchyma and replaces most of the kidney. In most cases, mesoblastic nephroma is benign and occurs in the fetus or newborn, and rarely in the older child or the adult."
      },
      "child_count": 1,
      "reference_id": "MONDO:0003130"
    },
    {
      "id": 7212,
      "label": "embryonal neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6798
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:688",
          "EFO:0005784",
          "MEDGEN:45034",
          "NCIT:C3264",
          "ONCOTREE:EMBT",
          "UMLS:C0027654"
        ],
        "synonyms": [
          "embryonal neoplasm",
          "embryonal tumor",
          "embryonal tumour",
          "EMBT",
          "embryonal cancer"
        ],
        "definition": "A usually malignant neoplasm composed of primitive (immature) tissues that resemble fetal tissues. Medulloblastoma, Ependymoblastoma, Pineoblastoma, and Wilms tumor are representative embryonal neoplasms. --2003"
      },
      "child_count": 12,
      "reference_id": "MONDO:0005564"
    },
    {
      "id": 22942,
      "label": "childhood malignant kidney neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4465,
        4767,
        8005
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:904186",
          "NCIT:C123907",
          "UMLS:C4086162"
        ],
        "synonyms": [
          "childhood kidney cancer",
          "childhood malignant kidney neoplasm",
          "childhood malignant kidney tumor",
          "childhood malignant kidney tumour",
          "childhood malignant renal neoplasm",
          "childhood malignant renal tumor",
          "childhood malignant renal tumour",
          "kidney cancer of childhood",
          "paediatric kidney cancer",
          "pediatric kidney cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A malignant neoplasm that affects the kidney and occurs in childhood."
      },
      "child_count": 9,
      "reference_id": "MONDO:0036511"
    }
  ],
  "children": [
    {
      "id": 6260,
      "label": "cellular congenital mesoblastic nephroma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17426
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8082",
          "GARD:0024015",
          "MEDGEN:729112",
          "NCIT:C39815",
          "UMLS:C1320471"
        ],
        "synonyms": [
          "cellular congenital mesoblastic nephroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A congenital mesoblastic nephroma characterized by increased cellularity, sheet-like proliferation of fibroblastic cells, and increased mitotic activity. Necrotic changes are commonly present."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004454"
    },
    {
      "id": 6261,
      "label": "classic congenital mesoblastic nephroma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17426
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8083",
          "GARD:0024016",
          "MEDGEN:273923",
          "NCIT:C39814",
          "UMLS:C1516475"
        ],
        "synonyms": [
          "classic congenital mesoblastic nephroma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A congenital mesoblastic nephroma characterized by the presence of interlacing fascicles of fibroblastic cells, low mitotic activity, and collagen formation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004455"
    }
  ],
  "roots": [
    {
      "id": 5106,
      "label": "mesoblastic nephroma"
    },
    {
      "id": 7212,
      "label": "embryonal neoplasm"
    },
    {
      "id": 22942,
      "label": "childhood malignant kidney neoplasm"
    }
  ]
}