{
  "id": 17472,
  "label": "isolated focal cortical dysplasia type I",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017095",
  "properties": {
    "xrefs": [
      "GARD:0020983",
      "MEDGEN:1843077",
      "Orphanet:268961",
      "UMLS:C5679772"
    ],
    "synonyms": [
      "FCD type I"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 18924,
      "label": "isolated focal cortical dysplasia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17471,
        24020
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016671",
          "MEDGEN:1645432",
          "NANDO:1200564",
          "Orphanet:65683",
          "SCTID:766710005",
          "UMLS:C4707795"
        ],
        "synonyms": [
          "epilepsy due to FCD"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Isolated focal cortical dysplasia is a rare, genetic, non-syndromic cerebral malformation due to abnormal neuronal migration disorder characterized by variable-sized, focalized malformations located in any part(s) of the cerebral cortex, which manifests with drug-resistant epilepsy (usually leading to intellectual disability) and behavioral disturbances. Abnormal MRI findings (e.g. abnormal white and/or gray matter signal, blurred gray-white matter junction, localized volume loss, cortical thickening, abnormal gyral pattern, abnormal hippocampus) and variable histopathologic patterns are associated."
      },
      "child_count": 4,
      "reference_id": "MONDO:0019009"
    }
  ],
  "children": [
    {
      "id": 17473,
      "label": "isolated focal cortical dysplasia type Ia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17472
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020984",
          "MEDGEN:1843115",
          "NANDO:1200565",
          "Orphanet:268973",
          "UMLS:C5679767"
        ],
        "synonyms": [
          "FCD type Ia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017096"
    },
    {
      "id": 17474,
      "label": "isolated focal cortical dysplasia type Ib",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17472
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020985",
          "MEDGEN:1842666",
          "NANDO:1200566",
          "Orphanet:268980",
          "UMLS:C5679765"
        ],
        "synonyms": [
          "FCD type IB"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017097"
    },
    {
      "id": 17475,
      "label": "isolated focal cortical dysplasia type Ic",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17472
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020986",
          "MEDGEN:1842276",
          "NANDO:1200567",
          "Orphanet:268987",
          "UMLS:C5679766"
        ],
        "synonyms": [
          "FCD type Ic"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017098"
    }
  ],
  "roots": [
    {
      "id": 18924,
      "label": "isolated focal cortical dysplasia"
    }
  ]
}