{
  "id": 17479,
  "label": "encephaloclastic disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017103",
  "properties": {
    "xrefs": [
      "GARD:0020987",
      "MEDGEN:1843179",
      "Orphanet:269190",
      "UMLS:C5680772",
      "icd11.foundation:1436588898"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 7209,
      "label": "brain disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4657
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:936",
          "EFO:0005774",
          "ICD9:348.3",
          "ICD9:348.30",
          "ICD9:348.8",
          "ICD9:348.9",
          "MEDGEN:14214",
          "MESH:D001927",
          "NCIT:C96413",
          "SCTID:81308009",
          "UMLS:C0006111"
        ],
        "synonyms": [
          "brain disease",
          "brain disease or disorder",
          "disease of brain",
          "disease or disorder of brain",
          "disorder of brain",
          "encephalopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disease affecting the brain or part of the brain."
      },
      "child_count": 71,
      "reference_id": "MONDO:0005560"
    }
  ],
  "children": [
    {
      "id": 11205,
      "label": "schizencephaly",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4427,
        17479
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0000166",
          "ICD9:742.4",
          "MEDGEN:78606",
          "MESH:D065707",
          "NANDO:1201073",
          "NANDO:2200818",
          "NCIT:C99056",
          "OMIM:269160",
          "Orphanet:799",
          "SCTID:253159001",
          "UMLS:C0266484",
          "icd11.foundation:1693546163"
        ],
        "synonyms": [
          "schizencephaly"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Schizencephaly is a rare congenital cerebral malformation characterized by the presence of linear clefts in one or both hemispheres of the brain, extending from the lateral ventricles to the pial surface of the cortex, and that lead to a variety of neurological symptoms such as epilepsy, motor deficits, and psychomotor retardation."
      },
      "child_count": 4,
      "reference_id": "MONDO:0010011"
    },
    {
      "id": 16882,
      "label": "hydranencephaly",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3145,
        17479
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4626",
          "GARD:0006681",
          "HP:0002324",
          "MEDGEN:6937",
          "MESH:D006832",
          "NCIT:C98949",
          "NORD:1258",
          "Orphanet:2177",
          "SCTID:30023002",
          "UMLS:C0020225",
          "icd11.foundation:1963574608"
        ],
        "synonyms": [
          "hydranencephaly",
          "hydranencephaly (disease)",
          "Hydroanencephaly"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare congenital brain disorder in which the cerebral hemispheres are absent and replaced by sacs that contain cerebrospinal fluid. Signs and symptoms include irritability, increased muscle tone, seizures, and hydrocephalus. The prognosis is poor."
      },
      "child_count": 2,
      "reference_id": "MONDO:0016344"
    },
    {
      "id": 17717,
      "label": "porencephaly",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17479
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060263",
          "GARD:0007430",
          "HP:0002132",
          "MEDGEN:901502",
          "MESH:D065708",
          "MedDRA:10036172",
          "NANDO:1201074",
          "Orphanet:2940",
          "UMLS:C4082173",
          "icd11.foundation:137059367"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Porencephaly is characterized by a circumscribed intracerebral cavity of variable size that may be bordered by abnormal polymicrogyric gray matter. In extreme cases, this cavity may result in a communication between the pial surface and the ventricle; this is termed schizencephaly."
      },
      "child_count": 2,
      "reference_id": "MONDO:0017410"
    }
  ],
  "roots": [
    {
      "id": 7209,
      "label": "brain disorder"
    }
  ]
}