{
  "id": 17566,
  "label": "autoimmune pancreatitis type 1",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017227",
  "properties": {
    "xrefs": [
      "EFO:1000780",
      "GARD:0021076",
      "MEDGEN:927912",
      "Orphanet:280302",
      "PMID:25985088",
      "SCTID:722872000",
      "UMLS:C4302243"
    ],
    "synonyms": [
      "AIP type 1",
      "IgG4-related pancreatitis",
      "autoimmune pancreatitis type 1",
      "lymphoplasmacytic sclerosing pancreatitis"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "Type 1 autoimmune pancreatitis is a form of autoimmune pancreatitis seen in elderly males (>60 years) and presenting with abdominal pain, steatorrhea, obstructive jaundice and other organ (bile duct, kidneys and retroperitoneum) involvement. It is thought to be due to an immunoglobulin G4 (IgG4)-associated systemic disease."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6741,
      "label": "chronic pancreatitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6723
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0051065",
          "EFO:0000342",
          "ICD9:577.1",
          "MEDGEN:101753",
          "MESH:D050500",
          "NCIT:C84637",
          "SCTID:235494005",
          "UMLS:C0149521",
          "icd11.foundation:1758007371"
        ],
        "synonyms": [
          "pancreatitis, chronic"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A chronic inflammatory process causing damage and fibrosis of the pancreatic parenchyma. Signs and symptoms include abdominal pain, malabsorption and diabetes mellitus."
      },
      "child_count": 3,
      "reference_id": "MONDO:0005003"
    },
    {
      "id": 16099,
      "label": "autoimmune pancreatitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2997,
        3004,
        6723,
        17611
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0040091",
          "GARD:0010911",
          "MEDGEN:750633",
          "MESH:D000081012",
          "MedDRA:10069002",
          "NANDO:1200925",
          "NANDO:2200943",
          "Orphanet:103919",
          "SCTID:448542008",
          "UMLS:C2609129",
          "icd11.foundation:2057951941"
        ],
        "synonyms": [
          "AIP",
          "lymphoplasmocytic sclerosing pancreatitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Autoimmune pancreatitis (AIP) is a rare pancreatic disease characterized by chronic non-alcoholic pancreatitis that presents with abdominal pain, steatorrhea, obstructive jaundice and responds well to steroid therapy and is seen in two subforms: type 1 AIP which affects elderly males, involves other organs and has increased immunoglobin G4 (IgG4) levels and type 2 AIP which affects both sexes equally but presents at a younger age and has no other organ involvement or increased IgG4 levels."
      },
      "child_count": 8,
      "reference_id": "MONDO:0015175"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6741,
      "label": "chronic pancreatitis"
    },
    {
      "id": 16099,
      "label": "autoimmune pancreatitis"
    }
  ]
}