{
  "id": 17589,
  "label": "panuveitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017255",
  "properties": {
    "xrefs": [
      "DOID:12030",
      "EFO:1001082",
      "GARD:0008577",
      "HP:0012121",
      "ICD10CM:H44.11",
      "ICD9:360.12",
      "MEDGEN:45303",
      "MESH:D015864",
      "MedDRA:10033687",
      "NCIT:C84989",
      "Orphanet:280898",
      "SCTID:75614007",
      "UMLS:C0030343",
      "icd11.foundation:1125547814"
    ],
    "synonyms": [
      "diffuse uveitis",
      "panuveitis",
      "panuveitis (disease)",
      "total uveitis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "A disorder characterized by inflammation of the entire uvea which includes the iris, ciliary body, and choroid. Causes include systemic infections, sarcoidosis, and cancers."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 19773,
      "label": "uveitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4712,
        20399
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13141",
          "EFO:1001231",
          "GARD:0019549",
          "HP:0000554",
          "MEDGEN:52961",
          "MESH:D014605",
          "MedDRA:10046851",
          "NCIT:C26909",
          "Orphanet:98715",
          "SCTID:128473001",
          "UMLS:C0042164"
        ],
        "synonyms": [
          "inflammation of uvea",
          "uvea inflammation",
          "uveitis",
          "uveitis (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "An inflammatory process affecting a part of or the entire uvea. Causes include inflammatory agents (e.g., herpes simplex, herpes zoster, leptospirosis) and systemic diseases (e.g., inflammatory bowel disease, multiple sclerosis, systemic lupus erythematosus, ankylosing spondylitis). Patients present with pain and redness in the eye, light sensitivity, and blurred and decreased vision."
      },
      "child_count": 18,
      "reference_id": "MONDO:0020283"
    }
  ],
  "children": [
    {
      "id": 17551,
      "label": "infectious panuveitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17589,
        23257
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021068",
          "MEDGEN:1684863",
          "Orphanet:279925",
          "UMLS:C5230354",
          "icd11.foundation:1709165622"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017211"
    },
    {
      "id": 17592,
      "label": "idiopathic panuveitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17589,
        24405
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021100",
          "MEDGEN:1633708",
          "Orphanet:280921",
          "SCTID:766933000",
          "UMLS:C4707884"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Idiopathic panuveitis is a rare inflammatory eye disease, of unknown etiology, characterized by generalized inflammation of the uvea (iris, ciliary body, choroid), retina and vitreous with consequent ciliary spasm and posterior synechiae formation, leading to acute or chronic, unilateral or bilateral visual impairment and ocular discomfort or pain. Patients present an increased risk of development of cataracts, secondary glaucoma, cystoid macular edema and/or retinal detachment. It could potentially result in vision loss."
      },
      "child_count": 2,
      "reference_id": "MONDO:0017258"
    },
    {
      "id": 18252,
      "label": "Vogt-Koyanagi-Harada disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17589
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12297",
          "GARD:0007862",
          "ICD10CM:H20.82",
          "ICD10CM:H30.81",
          "ICD9:363.22",
          "ICD9:364.24",
          "MEDGEN:22599",
          "MESH:D014607",
          "NCIT:C85218",
          "NORD:1829",
          "Orphanet:3437",
          "SCTID:193497004",
          "UMLS:C0042170"
        ],
        "synonyms": [
          "Harada's disease",
          "Uveomenigitic syndrome",
          "Vogt-Koyanagi syndrome",
          "uveomeningoencephalitic syndrome",
          "VKH disease",
          "VKH syndrome",
          "Vogt-Koyanagi-Harada syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A bilateral, chronic, diffuse granulomatous panuveitis typically characterized by serous retinal detachment and frequently associated with neurological (meningitis), auditory, and dermatological alterations."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018092"
    },
    {
      "id": 19068,
      "label": "sympathetic ophthalmia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17589,
        17907
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12029",
          "EFO:1001205",
          "GARD:0018939",
          "ICD10CM:H44.13",
          "ICD9:360.11",
          "MEDGEN:45203",
          "MESH:D009879",
          "MedDRA:10042742",
          "Orphanet:79098",
          "SCTID:75315001",
          "UMLS:C0029077",
          "icd11.foundation:1639718137"
        ],
        "synonyms": [
          "sympathetic ophthalmia",
          "sympathetic uveitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Sympathetic ophthalmia (SO) is a bilateral granulomatous anterior uveitis usually occurring within the three months following trauma or a surgical procedure involving one eye."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019198"
    }
  ],
  "roots": [
    {
      "id": 19773,
      "label": "uveitis"
    }
  ]
}