{
  "id": 17684,
  "label": "poliomyelitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017373",
  "properties": {
    "xrefs": [
      "DOID:4953",
      "EFO:0007450",
      "GARD:0007413",
      "ICD9:045",
      "ICD9:045.9",
      "ICD9:045.90",
      "ICD9:045.92",
      "MEDGEN:18545",
      "MESH:D011051",
      "MedDRA:10036012",
      "NCIT:C35550",
      "Orphanet:2912",
      "SCTID:398102009",
      "UMLS:C0032371",
      "icd11.foundation:588527933"
    ],
    "synonyms": [
      "Polia",
      "acute poliomyelitis",
      "polio",
      "poliomyelitis",
      "infantile paralysis"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "An acute infectious disorder that affects the nervous system. It is caused by the poliovirus. The virus spreads by direct contact, and can be prevented by prophylaxis with the polio vaccine."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4629,
      "label": "myelitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4611,
        6880
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:322",
          "EFO:1001472",
          "ICD9:323.9",
          "MEDGEN:10230",
          "MESH:D009187",
          "NCIT:C26832",
          "SCTID:41370002",
          "UMLS:C0026975",
          "icd11.foundation:1993728609"
        ],
        "synonyms": [
          "inflammation of spinal cord",
          "spinal cord inflammation"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An inflammatory process affecting the spinal cord. Causes include viral infections, autoimmune disorders, vascular disorders, and toxic agents. Symptoms include weakness, paresthesia, sensory loss, pain, and incontinence."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002565"
    },
    {
      "id": 5143,
      "label": "anterior horn disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4611
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4873",
          "ICD9:335",
          "MEDGEN:102314",
          "SCTID:85672005",
          "UMLS:C0154681"
        ],
        "synonyms": [
          "disease of ventral horn of spinal cord",
          "disease or disorder of ventral horn of spinal cord",
          "disorder of ventral horn of spinal cord",
          "ventral horn of spinal cord disease",
          "ventral horn of spinal cord disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Anterior horn disease is one of a number of medical disorders affecting the anterior horn of the spinal cord. Anterior horn diseases include spinal muscular atrophy, poliomyelitis and amyotrophic lateral sclerosis."
      },
      "child_count": 3,
      "reference_id": "MONDO:0003182"
    },
    {
      "id": 19750,
      "label": "acquired motor neuron disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19749
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019479",
          "MEDGEN:1842733",
          "Orphanet:98506",
          "UMLS:C5680367"
        ],
        "synonyms": [
          "acquired anterior horn cell disease",
          "acquired motor neuron disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An instance of motor neuron disease that is acquired during the lifetime of the individual."
      },
      "child_count": 3,
      "reference_id": "MONDO:0020129"
    },
    {
      "id": 20092,
      "label": "acute disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24492
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:1738",
          "MESH:D000208",
          "SCTID:2704003",
          "UMLS:C0001314"
        ],
        "synonyms": [
          "acute disease",
          "acute diseases",
          "disease, acute"
        ],
        "definition": "Disease having a short and relatively severe course."
      },
      "child_count": 119,
      "reference_id": "MONDO:0020683"
    },
    {
      "id": 21351,
      "label": "viral infection of central nervous system",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6834,
        21534
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025391",
          "ICD10CM:A80-A89",
          "ICD10WHO:A80-A89",
          "MEDGEN:91141",
          "MESH:D020805",
          "SCTID:302810003",
          "UMLS:C0348165"
        ],
        "synonyms": [
          "viral infection of central nervous system",
          "central nervous system viral infection",
          "viral disease of central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 14,
      "reference_id": "MONDO:0024318"
    },
    {
      "id": 21533,
      "label": "poliovirus infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7368
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:928804",
          "SCTID:721764008",
          "UMLS:C4303135"
        ],
        "synonyms": [
          "Enterovirus C caused disease or disorder",
          "Enterovirus C disease or disorder",
          "Enterovirus C infectious disease",
          "human poliovirus infection",
          "infection caused by human poliovirus"
        ],
        "definition": "An disease or disorder caused by infection with Enterovirus C."
      },
      "child_count": 2,
      "reference_id": "MONDO:0024618"
    }
  ],
  "children": [
    {
      "id": 2855,
      "label": "paralytic poliomyelitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17684
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050515",
          "GARD:0022753",
          "MEDGEN:1684656",
          "UMLS:C1405301"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A poliomyelitis that results in destruction located in motor neurons of central nervous system, has material basis in Human poliovirus 1, has material basis in Human poliovirus 2, or has material basis in Human poliovirus 3, which are transmitted by ingestion of food or water contaminated with feces, or transmitted by direct contact with the oral secretions. The infection has symptom loss of reflexes, has symptom muscle spasms, and has symptom acute flaccid paralysis."
      },
      "child_count": 3,
      "reference_id": "MONDO:0000341"
    },
    {
      "id": 5179,
      "label": "acute nonparalytic poliomyelitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17684
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4986",
          "GARD:0023415",
          "ICD10CM:A80.4",
          "ICD9:045.2",
          "ICD9:045.20",
          "ICD9:045.22",
          "ICD9:045.23",
          "MEDGEN:509107",
          "SCTID:14535005",
          "UMLS:C0152998",
          "icd11.foundation:1066160874"
        ],
        "synonyms": [
          "acute nonparalytic poliomyelitis",
          "non-paralytic aseptic meningitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A poliomyelitis that does not exhibit paralysis."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003231"
    },
    {
      "id": 17721,
      "label": "postpoliomyelitis syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17684
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4952",
          "EFO:0007454",
          "GARD:0004454",
          "ICD10CM:G14",
          "MEDGEN:36363",
          "MESH:D016262",
          "NORD:1600",
          "Orphanet:2942",
          "SCTID:31097004",
          "UMLS:C0080040",
          "icd11.foundation:2018885243"
        ],
        "synonyms": [
          "Post Polio Syndrome",
          "postpolio sequelae",
          "postpolio syndrome",
          "postpoliomyelitic syndrome",
          "postpoliomyelitis sequelae",
          "postpoliomyelitis syndrome",
          "polio late effects",
          "post polio syndrome",
          "post-polio muscular atrophy",
          "post-polio sequelae",
          "post-poliomyelitic syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Postpoliomyelitis syndrome (PPS) is a neurologic disorder characterized by the development of new neuromuscular symptoms such as progressive muscular weakness or abnormal muscle fatigability occurring in survivors of the acute paralytic form of poliomyelitis, 15-40 years after recovery from the disease, and that is unexplained by other medical causes. Other manifestations that can occur gradually include generalized fatigue, muscle atrophy, muscle and joint pain, intolerance to cold, and difficulties sleeping, swallowing or breathing."
      },
      "child_count": 0,
      "reference_id": "MONDO:0017416"
    }
  ],
  "roots": [
    {
      "id": 4629,
      "label": "myelitis"
    },
    {
      "id": 5143,
      "label": "anterior horn disorder"
    },
    {
      "id": 19750,
      "label": "acquired motor neuron disease"
    },
    {
      "id": 20092,
      "label": "acute disease"
    },
    {
      "id": 21351,
      "label": "viral infection of central nervous system"
    },
    {
      "id": 21533,
      "label": "poliovirus infection"
    }
  ]
}