{
  "id": 17696,
  "label": "epithelioid sarcoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017387",
  "properties": {
    "xrefs": [
      "DOID:6193",
      "GARD:0010181",
      "ICDO:8804/3",
      "MEDGEN:104753",
      "MedDRA:10015099",
      "NCIT:C3714",
      "ONCOTREE:EPIS",
      "Orphanet:293202",
      "UMLS:C0205944"
    ],
    "synonyms": [
      "ES",
      "epithelioid cell sarcoma",
      "epithelioid sarcoma"
    ],
    "definition": "An aggressive malignant neoplasm of uncertain differentiation, characterized by the presence of epithelioid cells forming nodular patterns. The nodules often undergo central necrosis, resulting in a pseudogranulomatous growth pattern. It usually occurs in young adults. The most common sites of involvement are the extremities (distal-type epithelioid sarcoma), and less frequently the pelvis, perineum, and genital organs (proximal-type epithelioid sarcoma)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 18239,
      "label": "soft tissue sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6816,
        21548
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070663",
          "EFO:1001968",
          "GARD:0004898",
          "MEDGEN:1642116",
          "NCIT:C9306",
          "NORD:1953",
          "Orphanet:3394",
          "SCTID:424952003",
          "UMLS:C4551687"
        ],
        "synonyms": [
          "malignant soft tissue tumor",
          "malignant soft tissue tumour",
          "connective tissue sarcoma",
          "malignant mesenchymal tumor",
          "malignant mesenchymal tumour",
          "non-Rhabdo. soft tissue sarcoma",
          "sarcoma of soft tissue",
          "sarcoma of the soft tissue",
          "soft part sarcoma",
          "soft tissue sarcoma"
        ],
        "definition": "A malignant neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones."
      },
      "child_count": 92,
      "reference_id": "MONDO:0018078"
    }
  ],
  "children": [
    {
      "id": 5901,
      "label": "peripheral epithelioid sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17696
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6988",
          "GARD:0023799",
          "MEDGEN:232131",
          "NCIT:C27473",
          "UMLS:C1333306"
        ],
        "synonyms": [
          "conventional epithelioid sarcoma",
          "distal-type epithelioid sarcoma"
        ],
        "definition": "An epithelioid sarcoma involving the extremities. It usually presents as nodular masses in the dermis and subcutaneous tissues or in the tendons and fascia. It frequently recurs and metastasizes to other anatomic sites. The most common sites of metastasis are the lungs, lymph nodes, bones, and brain."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004060"
    },
    {
      "id": 5939,
      "label": "childhood epithelioid sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8005,
        17696
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7095",
          "GARD:0023826",
          "MEDGEN:76055",
          "NCIT:C8095",
          "UMLS:C0279989"
        ],
        "synonyms": [
          "epithelioid sarcoma",
          "childhood epithelioid sarcoma",
          "epithelioid sarcoma of childhood",
          "paediatric epithelioid sarcoma",
          "pediatric epithelioid sarcoma"
        ],
        "definition": "An epithelioid sarcoma occurring in childhood."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004105"
    },
    {
      "id": 6065,
      "label": "proximal-type epithelioid sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17696
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7492",
          "GARD:0023896",
          "MEDGEN:235511",
          "NCIT:C27472",
          "ONCOTREE:PTES",
          "UMLS:C1335563"
        ],
        "synonyms": [
          "central epithelioid sarcoma",
          "proximal-type epithelioid sarcoma",
          "PTES"
        ],
        "definition": "An epithelioid sarcoma predominantly involving the pelvis, perineum, and genital organs. It tends to have a more aggressive clinical course as compared to the more frequently seen distal-type epithelioid sarcoma."
      },
      "child_count": 1,
      "reference_id": "MONDO:0004244"
    },
    {
      "id": 6322,
      "label": "adult epithelioid sarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17696
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8282",
          "GARD:0024048",
          "MEDGEN:124631",
          "NCIT:C7944",
          "UMLS:C0279545"
        ],
        "synonyms": [
          "epithelioid sarcoma",
          "adult epithelioid sarcoma",
          "epithelioid sarcoma of adults"
        ],
        "definition": "An epithelioid sarcoma occurring in adults."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004521"
    }
  ],
  "roots": [
    {
      "id": 18239,
      "label": "soft tissue sarcoma"
    }
  ]
}