{
  "id": 17872,
  "label": "staphylococcal toxemia",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017592",
  "properties": {
    "xrefs": [
      "GARD:0021239",
      "MEDGEN:799765",
      "MedDRA:10041932",
      "Orphanet:300579",
      "UMLS:C0854511"
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 5,
  "parents": [
    {
      "id": 21346,
      "label": "staphylococcal infection",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6839
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1001849",
          "MEDGEN:52483",
          "MESH:D013203",
          "NCIT:C35038",
          "SCTID:56038003",
          "UMLS:C0038160"
        ],
        "synonyms": [
          "staphylococcal infection"
        ],
        "definition": "An infection caused by Staphylococcus."
      },
      "child_count": 4,
      "reference_id": "MONDO:0024313"
    }
  ],
  "children": [
    {
      "id": 18322,
      "label": "staphylococcal scarlet fever",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17872
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018819",
          "MEDGEN:1853264",
          "Orphanet:36235",
          "UMLS:C5848379",
          "icd11.foundation:449652676"
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0018180"
    },
    {
      "id": 18323,
      "label": "staphylococcal scalded skin syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2838,
        7197,
        17872,
        21329
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9063",
          "EFO:0007473",
          "GARD:0013158",
          "ICD10CM:L00",
          "ICD10WHO:L00",
          "ICD9:695.81",
          "MEDGEN:52484",
          "MESH:D013206",
          "MedDRA:10041929",
          "NCIT:C85077",
          "NORD:1781",
          "Orphanet:36236",
          "SCTID:200946001",
          "SCTID:277475006",
          "UMLS:C0038165",
          "icd11.foundation:1554593739"
        ],
        "synonyms": [
          "Ritter disease",
          "Ritter's disease",
          "SSSS",
          "generalised exfoliative disease",
          "generalized exfoliative disease",
          "staphylococcal scalded skin syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A blistering skin disorder caused by exfoliative toxins produced by Staphylococcus aureus infection. The toxins cause the formation of bullae and diffuse skin desquamation. The lesions may be localized or generalized, far away from the initial site of infection."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018181"
    },
    {
      "id": 18324,
      "label": "bullous impetigo",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17872,
        21329
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018820",
          "ICD10CM:L01.03",
          "MEDGEN:507838",
          "MedDRA:10006563",
          "Orphanet:36237",
          "SCTID:399183005",
          "UMLS:C0021100",
          "icd11.foundation:1398484288"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Bullous impetigo is a contagious superficial infection occurring in intact skin. Prevalence in the general population is unknown. The disease is characterized by fragile vesicles and flaccid blisters, most often presenting as erosive lesions covered by a yellow crust. The face, trunk and extremities of children under 5 years of age (particularly neonates) are mainly affected. The disease is generally caused by group II Staphylococcus aureus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018182"
    },
    {
      "id": 18325,
      "label": "staphylococcal necrotizing pneumonia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6815,
        17872
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018821",
          "MEDGEN:1637863",
          "Orphanet:36238",
          "SCTID:763888005",
          "UMLS:C4706659"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Staphylococcal necrotizing pneumonia is a rare, bacterial, pulmonary infectious disease, caused by a Panton-Valentine leukocidin-producing Staphylococcus aureus strain, characterized by severe respiratory failure, extensive, rapidly progressing pneumonia and hemorrhagic lung necrosis. Patients typically present with influenza-like symptoms, such as fever, cough, and chest pain, as well as hemoptysis, hypotension, leukopenia, and severe respiratory symptoms that rapidly evolve to acute respiratory distress syndrome and septic shock. High mortality is associated."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018183"
    },
    {
      "id": 19989,
      "label": "staphylococcal toxic-shock syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4056,
        17872
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019710",
          "ICD9:040.89",
          "MEDGEN:811401",
          "MedDRA:10044250",
          "Orphanet:99919",
          "SCTID:240450004",
          "UMLS:C3714602",
          "icd11.foundation:788554020"
        ],
        "synonyms": [
          "Staphylococcus caused toxic shock syndrome",
          "Staphylococcus toxic shock syndrome",
          "staphylococcal TSS"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "Staphylococcal toxic shock syndrome (staphylococcal TSS) is an acute disease mediated by the production of superantigenic toxins, characterized by high fever, skin rash followed by skin peeling, hypotension, vomiting, diarrhea and potentially leading to multisystem organ failure and caused by a Staphylococcus aureus bacterial infection."
      },
      "child_count": 0,
      "reference_id": "MONDO:0020545"
    }
  ],
  "roots": [
    {
      "id": 21346,
      "label": "staphylococcal infection"
    }
  ]
}