{
  "id": 17876,
  "label": "diffuse large B-cell lymphoma of the central nervous system",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017596",
  "properties": {
    "xrefs": [
      "DOID:0081313",
      "GARD:0021246",
      "ICDO:9680/3",
      "MEDGEN:378339",
      "NCIT:C71720",
      "Orphanet:300849",
      "SCTID:734066005",
      "UMLS:C2026186",
      "icd11.foundation:1029172881"
    ],
    "synonyms": [
      "CNS DLBCL",
      "DLBCL of the CNS",
      "central nervous system diffuse large B-cell lymphoma",
      "diffuse large B-cell lymphoma of central nervous system",
      "primary DLBCL of the CNS",
      "primary diffuse large B-cell lymphoma of the central nervous system"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A diffuse large B-cell lymphoma arising from the central nervous system."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18833,
      "label": "diffuse large B-cell lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6694,
        17875
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050745",
          "EFO:0000403",
          "GARD:0003178",
          "ICD10CM:C83.3",
          "ICD9:200.7",
          "ICDO:9680/3",
          "MEDGEN:86954",
          "MESH:D016403",
          "MedDRA:10012818",
          "NCIT:C8851",
          "Orphanet:544",
          "UMLS:C0079744",
          "icd11.foundation:1946973604"
        ],
        "synonyms": [
          "DLBCL",
          "diffuse large B-cell lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Diffuse large B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma (NHL) in adults characterized by a median age of presentation in the sixth decade of life (but also rarely occurring in adolescents and children) with the initial presentation being single or multiple rapidly growing masses (that may or may not be painful) in nodal or extranodal sites (such as thyroid, skin, breast, gastrointestinal tract, testes, bone, or brain) and that can be accompanied by symptoms of fever, night sweats and weight loss. DLBCL has an aggressive disease course, with the elderly having a poorer prognosis than younger patients, and with relapses being common."
      },
      "child_count": 60,
      "reference_id": "MONDO:0018905"
    },
    {
      "id": 23470,
      "label": "central nervous system non-hodgkin lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4634,
        16516
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025918",
          "MEDGEN:745669",
          "NCIT:C114779",
          "SCTID:448254007",
          "UMLS:C2213246"
        ],
        "synonyms": [
          "Central nervous system non-Hodgkin lymphoma",
          "Primary Central nervous system non-Hodgkin lymphoma",
          "central nervous system non-Hodgkin lymphoma",
          "non-Hodgkin lymphoma of central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A non-Hodgkin lymphoma that arises from the central nervous system."
      },
      "child_count": 4,
      "reference_id": "MONDO:0044887"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18833,
      "label": "diffuse large B-cell lymphoma"
    },
    {
      "id": 23470,
      "label": "central nervous system non-hodgkin lymphoma"
    }
  ]
}