{
  "id": 17882,
  "label": "ALK-positive anaplastic large cell lymphoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017602",
  "properties": {
    "xrefs": [
      "GARD:0021251",
      "ICD10CM:C84.6",
      "ICDO:9714/3",
      "MEDGEN:233117",
      "NCIT:C37193",
      "Orphanet:300895",
      "UMLS:C1332079"
    ],
    "synonyms": [
      "ALCL, ALK+",
      "ALK+ ALCL",
      "ALK+ anaplastic large cell lymphoma",
      "ALK-positive anaplastic large cell lymphoma",
      "ALKoma",
      "anaplastic large cell lymphoma, ALK-positive"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "ALK-positive anaplastic large cell lymphoma (ALK+ ALCL) is a type of ALCL, a rare and aggressive peripheral T-cell non-Hodgkin lymphoma affecting lymph nodes and extranodal sites, which is characterized by the expression of a protein called anaplastic lymphoma kinase (ALK)."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 19798,
      "label": "anaplastic large cell lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2906
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050744",
          "EFO:0003032",
          "GARD:0003112",
          "HGNC:427",
          "ICD9:200.6",
          "ICD9:200.60",
          "ICDO:9714/3",
          "MEDGEN:61533",
          "MESH:D017728",
          "NANDO:2200021",
          "NCIT:C3720",
          "ONCOTREE:ALCL",
          "Orphanet:98841",
          "SCTID:277637000",
          "UMLS:C0206180"
        ],
        "synonyms": [
          "ALCL",
          "CD30 Positive anaplastic large cell lymphoma",
          "CD30 positive anaplastic large cell lymphoma",
          "Ki-1 lymphoma",
          "Ki-1 positive anaplastic large cell lymphoma",
          "Ki-1+ ALCL",
          "Ki-1+ anaplastic large cell lymphoma",
          "anaplastic large cell lymphoma",
          "primary systemic ALCL",
          "sACL"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Anaplastic large cell lymphoma (ALCL) is a rare and aggressive peripheral T-cell non-Hodgkin lymphoma, belonging to the group of CD30-positive lymphoproliferative disorders, which affects lymph nodes and extranodal sites. It is comprised of two sub-types, based on the expression of a protein called anaplastic lymphoma kinase (ALK): ALK positive and ALK negative ALCL."
      },
      "child_count": 5,
      "reference_id": "MONDO:0020325"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 19798,
      "label": "anaplastic large cell lymphoma"
    }
  ]
}