{
  "id": 17909,
  "label": "manganese poisoning",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017638",
  "properties": {
    "xrefs": [
      "EFO:1001808",
      "GARD:0021264",
      "ICD9:503",
      "MESH:D020149",
      "MedDRA:10058951",
      "Orphanet:306682",
      "SCTID:88687001"
    ],
    "synonyms": [
      "Manganism",
      "manganese intoxication"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Manganese poisoning is associated with chronic inhalation of manganese particles by individuals who work with manganese ore. Clinical features include confusion; hallucinations; and an extrapyramidal syndrome (Parkinson disease, secondary) that includes rigidity; dystonia; retropulsion; and tremor. (Adams, Principles of Neurology, 6th ed, p1213)"
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 7181,
      "label": "toxic encephalopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6799
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3602",
          "EFO:0005595",
          "GARD:0007199",
          "ICD10CM:G92",
          "ICD10WHO:G92",
          "ICD9:349.82",
          "MESH:D020258",
          "NCIT:C27961",
          "SCTID:28394000",
          "Wikipedia:Toxic_encephalopathy"
        ],
        "synonyms": [
          "neurotoxicity",
          "neurotoxicity syndrome",
          "neurotoxicity syndromes"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A group of neurologic disorders caused by damage to the nervous system following exposure to pharmacologic, biologic, and chemical agents. Examples of neurotoxins include chemotherapy agents, radiation treatment, heavy metals, pesticides, and food additives."
      },
      "child_count": 5,
      "reference_id": "MONDO:0005527"
    },
    {
      "id": 21773,
      "label": "poisoning",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0008546",
          "MESH:D011041",
          "SCTID:75478009"
        ],
        "synonyms": [
          "Poisonings",
          "intoxication",
          "poisoning syndrome"
        ],
        "definition": "A condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent."
      },
      "child_count": 59,
      "reference_id": "MONDO:0029000"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 7181,
      "label": "toxic encephalopathy"
    },
    {
      "id": 21773,
      "label": "poisoning"
    }
  ]
}