{
  "id": 17911,
  "label": "cyanide-induced parkinsonism",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017640",
  "properties": {
    "xrefs": [
      "GARD:0021266",
      "MEDGEN:1639789",
      "Orphanet:306692",
      "SCTID:766872002",
      "UMLS:C4707859",
      "icd11.foundation:1717111858"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Cyanide-induced parkinsonism is a rare parkinsonian syndrome due to intoxication which develops in individuals surviving an acute cyanide intoxication episode or due to chronic exposure to small cyanide doses. It presents several weeks after acute exposure with progressive typical clinical features of parkinsonism including bradykinesia, rigidity, dystonia, hypomimia, hypokinetic dysarthria, postural instability and retropulsion but no resting or postural tremor. Brain MRI reveals bilateral lesions in the pallidum, posterior putamen, substantia nigra, subthalamic nucleus, temporal and occipital cortex, and cerebellum."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 20335,
      "label": "parkinsonian disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5849
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080855",
          "MEDGEN:66079",
          "MESH:D020734",
          "UMLS:C0242422"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA."
      },
      "child_count": 21,
      "reference_id": "MONDO:0021095"
    },
    {
      "id": 21773,
      "label": "poisoning",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0008546",
          "MESH:D011041",
          "SCTID:75478009"
        ],
        "synonyms": [
          "Poisonings",
          "intoxication",
          "poisoning syndrome"
        ],
        "definition": "A condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent."
      },
      "child_count": 59,
      "reference_id": "MONDO:0029000"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 20335,
      "label": "parkinsonian disorder"
    },
    {
      "id": 21773,
      "label": "poisoning"
    }
  ]
}