{
  "id": 17993,
  "label": "reflex epilepsy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017768",
  "properties": {
    "xrefs": [
      "DOID:2548",
      "EFO:1001146",
      "GARD:0018688",
      "ICD9:345.10",
      "MEDGEN:75726",
      "MESH:D020195",
      "NCIT:C85041",
      "Orphanet:310",
      "SCTID:79745005",
      "UMLS:C0270857",
      "icd11.foundation:276807111"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Reflex epilepsy refers to epilepsies where recurrent seizures are provoked by a clearly defined extrinsic (most commonly) or intrinsic triggering stimuli such as flashing lights (photosensitive epilepsy), startling noises (startle epilepsy), urinating (micturition induced seizures), exposure to hot-water (hot water epilepsy), eating, reading, and thinking, while being associated with an enduring abnormal predisposition to have such seizures (thereby meeting the conceptual definition of epilepsy)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 10,
  "parents": [
    {
      "id": 6761,
      "label": "epilepsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7209
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1826",
          "EFO:0000474",
          "ICD10CM:G40",
          "ICD10WHO:G40",
          "ICD9:345",
          "ICD9:345.8",
          "ICD9:345.80",
          "ICD9:345.9",
          "ICD9:345.90",
          "ICD9:345.91",
          "MEDGEN:4506",
          "MESH:D004827",
          "NCIT:C3020",
          "SCTID:84757009",
          "UMLS:C0014544",
          "birnlex:12718"
        ],
        "synonyms": [
          "epilepsy",
          "seizure disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions."
      },
      "child_count": 13,
      "reference_id": "MONDO:0005027"
    }
  ],
  "children": [
    {
      "id": 3608,
      "label": "visual epilepsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5479,
        17993
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11832",
          "GARD:0022931",
          "MEDGEN:75723",
          "MESH:D012640",
          "NCIT:C3980",
          "SCTID:39194005",
          "UMLS:C0270824"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as epilepsy or 'seizure disorder.'"
      },
      "child_count": 4,
      "reference_id": "MONDO:0001386"
    },
    {
      "id": 4443,
      "label": "tactile epilepsy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17993
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2550",
          "GARD:0023121",
          "MEDGEN:97960",
          "NCIT:C4687",
          "SCTID:230449001",
          "UMLS:C0393724"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0002340"
    },
    {
      "id": 8940,
      "label": "reading seizures",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17993,
        25078
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0017029",
          "MEDGEN:75817",
          "OMIM:132300",
          "Orphanet:166433",
          "UMLS:C0278193"
        ],
        "synonyms": [
          "EwRIS",
          "epilepsy with reading-induced seizures",
          "epilepsy, reading"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare reflex epilepsy characterized by reading-induced seizures which in most cases present with orofacial/jaw myoclonus possibly extending to the upper limbs but can also manifest as dyslexia or alexia and visual symptoms. In both variants secondary generalized tonic-clonic seizures may evolve if the stimulus is not interrupted. The disease typically begins in the second or third decade of life and may be inherited in an autosomal dominant pattern. It usually takes a benign course with little tendency to spontaneous seizures."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007560"
    },
    {
      "id": 16430,
      "label": "audiogenic seizures",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17993
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020077",
          "MEDGEN:155927",
          "Orphanet:166415",
          "SCTID:765216006",
          "UMLS:C0751791"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Audiogenic seizures is a rare neurologic disease characterized by seizures that are triggered by acoustic stimulation, which can be simple (as in startle epilepsy) or complex (e.g. musicogenic seizures, seizures triggered by the voice)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015644"
    },
    {
      "id": 16431,
      "label": "eating seizures",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17993
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020078",
          "MEDGEN:581543",
          "Orphanet:166418",
          "SCTID:230450001",
          "UMLS:C0393725"
        ],
        "synonyms": [
          "eating epilepsy",
          "eating reflex epilepsy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare reflex epilepsy characterized by in most cases complex partial seizures triggered by different components of eating, such as the sight of food, proprioceptive, olfactory or gustatory sensations, chewing, salivation, and gastric distension after food intake. The seizures may be idiopathic or associated with symptomatic localization-related epilepsies."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015645"
    },
    {
      "id": 16432,
      "label": "orgasm-induced seizures",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17993
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020079",
          "MEDGEN:1633277",
          "Orphanet:166421",
          "UMLS:C4706598"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Orgasm-induced seizures is a rare neurologic disease characterized by complex partial seizures with or without secondary generalization, or idiopathic primarily generalized epilepsy, triggered by sexual orgasm. Seizures usually start immediately, shortly after or a few hours after the achievement of orgasm, last a few seconds or minutes, and are followed, in very rare cases, by intense migraine."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015646"
    },
    {
      "id": 16433,
      "label": "thinking seizures",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17993
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020080",
          "MEDGEN:1647683",
          "Orphanet:166424",
          "SCTID:763622006",
          "UMLS:C4706523"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Thinking seizures is a rare neurologic disease characterized by seizures induced by specific cognitive tasks, such as calculation or solving arithmetic problems (e.g Sudoku puzzle), playing thinking games (e.g. Rubik's cube, chess, cards), thinking, making decisions and abstract reasoning. Idiopathic generalized seizures are mainly involved, but partial epilepsies may, in rare cases, be observed."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015647"
    },
    {
      "id": 16434,
      "label": "startle epilepsy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17993
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020081",
          "MEDGEN:1633187",
          "Orphanet:166427",
          "SCTID:763632004",
          "UMLS:C4706527",
          "icd11.foundation:1012101161"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Startle epilepsy is a rare neurologic disease characterized by frequent and spontaneous epileptic seizures (frequently with symmetrical or asymmetrical tonic features) triggered by a normal startle in response to a sudden and unexpected somatosensory (most frequently auditory) stimulus. Falls are common and can be traumatic. In most cases, the disease is associated with spastic hemi-, di-, or tetraplegia and intellectual disability."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015648"
    },
    {
      "id": 16435,
      "label": "micturation-induced seizures",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17993
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020082",
          "MEDGEN:1646690",
          "Orphanet:166430",
          "UMLS:C4706587"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Micturition-induced seizures is a rare neurologic disease characterized by tonic posturing or clonic movements triggered by micturition, with bilateral or unilateral involvement of the extremities and with or without loss of consciousness. Developmental delay is reported in some cases."
      },
      "child_count": 0,
      "reference_id": "MONDO:0015649"
    },
    {
      "id": 21188,
      "label": "inherited reflex epilepsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17993,
        24270
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "hereditary reflex epilepsy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An instance of reflex epilepsy that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 4,
      "reference_id": "MONDO:0023224"
    }
  ],
  "roots": [
    {
      "id": 6761,
      "label": "epilepsy"
    }
  ]
}