{
  "id": 18035,
  "label": "primary bone lymphoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0017814",
  "properties": {
    "xrefs": [
      "DOID:6759",
      "GARD:0021385",
      "MEDGEN:231451",
      "NCIT:C6620",
      "Orphanet:314684",
      "SCTID:766935007",
      "UMLS:C1332582"
    ],
    "synonyms": [
      "bone tissue lymphoma",
      "lymphoma of bone tissue",
      "primary lymphoma of bone",
      "primary lymphoma of the bone",
      "bone lymphoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A rare non-Hodgkin lymphoma or even more rarely, a Hodgkin lymphoma that arises from the bone, without lymph node or other extranodal involvement. The femur, spine, and pelvic bones are the most commonly affected sites. The majority of patients present with bone pain in the affected area. A single bone or multiple skeletal sites may be involved. The prognosis is related to the cell type and the stage of the disease."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4262,
      "label": "bone cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3041,
        18958
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "CSP:2019-1041",
          "DOID:184",
          "EFO:1000350",
          "GARD:0023070",
          "ICD9:170.9",
          "MEDGEN:79002",
          "MESH:D001859",
          "NCIT:C4016",
          "SCTID:428281000",
          "UMLS:C0279530"
        ],
        "synonyms": [
          "bone neoplasm",
          "bone tumor",
          "bone tumour",
          "osseous tumor",
          "osseous tumour",
          "bone cancer",
          "cancer of bone",
          "cancer of skeletal element",
          "cancer of the bone",
          "malignant bone neoplasm",
          "malignant bone tumor",
          "malignant neoplasm of bone",
          "malignant neoplasm of skeletal element",
          "malignant neoplasm of the bone",
          "malignant osseous neoplasm",
          "malignant osseous tumor",
          "malignant osseous tumour",
          "malignant skeletal element neoplasm",
          "malignant tumor of bone",
          "malignant tumor of the bone",
          "malignant tumour of bone",
          "malignant tumour of the bone",
          "osseous cancer",
          "skeletal element cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          }
        ],
        "definition": "A primary or metastatic malignant neoplasm affecting the bone or articular cartilage."
      },
      "child_count": 24,
      "reference_id": "MONDO:0002129"
    },
    {
      "id": 17548,
      "label": "primary organ-specific lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021064",
          "MEDGEN:1826175",
          "NCIT:C7185",
          "Orphanet:279911",
          "UMLS:C5680788"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 8,
      "reference_id": "MONDO:0017207"
    }
  ],
  "children": [
    {
      "id": 3929,
      "label": "paranasal sinus lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18035,
        20081
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1355",
          "GARD:0023000",
          "MEDGEN:277498",
          "NCIT:C6068",
          "UMLS:C1335339"
        ],
        "synonyms": [
          "accessory sinus lymphoma",
          "lymphoma of accessory sinus",
          "lymphoma of paranasal sinus",
          "lymphoma of the accessory sinus",
          "lymphoma of the paranasal sinus",
          "paranasal sinus lymphoma",
          "primary paranasal sinus lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A lymphoma that arises from the paranasal sinus. Representative examples include diffuse large B-cell lymphoma and extranodal NK/T-cell lymphoma, nasal type."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001743"
    },
    {
      "id": 5841,
      "label": "sternum lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5214,
        18035
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6762",
          "GARD:0023763",
          "MEDGEN:277770",
          "NCIT:C6716",
          "UMLS:C1336504"
        ],
        "synonyms": [
          "lymphoma of sternum",
          "lymphoma of the sternum",
          "primary sternal lymphoma",
          "sternal lymphoma",
          "sternum lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A rare lymphoma that arises from the bone or soft tissue of the sternum."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003988"
    },
    {
      "id": 19795,
      "label": "acute biphenotypic leukemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6710,
        18035,
        20146
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9953",
          "EFO:1000828",
          "GARD:0025156",
          "ICD9:207.80",
          "ICDO:9805/3",
          "MEDGEN:7318",
          "MESH:D015456",
          "MedDRA:10067399",
          "NCIT:C4673",
          "Orphanet:98837",
          "SCTID:278453007",
          "UMLS:C0023464"
        ],
        "synonyms": [
          "B- and T-cell mixed leukaemia",
          "B- and T-cell mixed leukemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An acute leukemia of ambiguous lineage characterized by blasts which coexpress myeloid and T or B lineage antigens or concurrent B and T lineage antigens. (WHO, 2001)"
      },
      "child_count": 12,
      "reference_id": "MONDO:0020322"
    }
  ],
  "roots": [
    {
      "id": 4262,
      "label": "bone cancer"
    },
    {
      "id": 17548,
      "label": "primary organ-specific lymphoma"
    }
  ]
}